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Generic Aurogra Information
Introduction
Aurogra is a medication used primarily to treat erectile dysfunction (ED) in adult men. It contains the active compound sildenafil, which belongs to the class of phosphodiesterase‑5 (PDE5) inhibitors. In the United Kingdom, erectile dysfunction affects an estimated 20 % of men aged 40 years and older, creating a significant demand for safe and effective therapies. Aurogra provides a pharmacologically proven option for restoring erectile function and improving quality of life.
What is Aurogra?
Aurogra is a tablet formulation that delivers sildenafil, the same molecule found in the well‑known brand Viagra® and other licensed PDE5 inhibitors. It is marketed as a cost‑effective alternative, manufactured under Good Manufacturing Practice (GMP) standards for oral use in men with erectile dysfunction. The product is classified as a prescription‑only medicine (POM) in the UK, but it can be obtained through licensed pharmacy‑broker services that source the drug from overseas, fully compliant with UK import regulations.
How Aurogra Works
Sildenafil blocks the enzyme phosphodiesterase‑5, which normally degrades cyclic guanosine monophosphate (cGMP) in the smooth muscle of the corpus cavernosum. During sexual stimulation, nitric oxide released from nerve endings increases cGMP levels, causing smooth‑muscle relaxation and inflow of blood to the penis. By inhibiting PDE5, Aurogra sustains higher cGMP concentrations, enhancing erection quality. The drug is absorbed within 30–60 minutes, reaches peak plasma concentrations in about one hour, and has an elimination half‑life of roughly 4 hours. Typical therapeutic effects last up to 12 hours, allowing a flexible window for sexual activity.
Conditions Treated with Aurogra
- Erectile Dysfunction (ED): The primary indication. ED prevalence in the UK rises with age, affecting 1 in 5 men over 40 and up to 1 in 3 men over 70. Sildenafil improves erectile response in men with vascular, neurogenic, or psychogenic causes of ED.
- Pulmonary Arterial Hypertension (PAH) (off‑label in some jurisdictions): Sildenafil’s vasodilatory effect on pulmonary vessels can lower pulmonary arterial pressure. Though not routinely prescribed for PAH in the UK, clinicians may consider it where approved alternatives are unavailable.
The drug is ineffective for erectile problems unrelated to vascular mechanisms, such as severe hormonal deficiencies that require endocrine therapy.
Who is Aurogra For?
- Men aged 18 years and older with a clinical diagnosis of erectile dysfunction who have stable cardiovascular status.
- Individuals who respond to PDE5 inhibition after trial of lower‑dose sildenafil or other PDE5 inhibitors.
- Patients without contraindicated medications such as nitrates or potent CYP3A4 inhibitors.
Aurogra is not appropriate for men with:
- Unstable angina, recent myocardial infarction, or severe uncontrolled hypertension.
- Congenital or acquired conditions predisposing to priapism (e.g., sickle‑cell disease).
- Severe hepatic or renal impairment without dose adjustment.
Risks, Side Effects, and Interactions
Common
- Headache
- Facial flushing
- Indigestion or dyspepsia
- Nasal congestion
- Vision changes (blurred vision, colour tinge)
Rare
- Priapism (prolonged erection lasting > 4 hours)
- Sudden hearing loss or tinnitus
- Myocardial ischaemia in patients with existing coronary disease
- Severe hypotension, especially when combined with nitrates
Serious
- Persistent priapism requiring emergency medical intervention
- Non‑arteritic anterior ischemic optic neuropathy (sudden vision loss)
- Life‑threatening hypotensive episodes
Clinically Relevant Drug–Drug Interactions
- Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Concomitant use can cause profound vasodilation and fatal hypotension.
- Alpha‑blockers (e.g., tamsulosin, doxazosin): May potentiate blood‑pressure lowering effects; dose titration is required.
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin, ritonavir): Increase sildenafil plasma levels, raising the risk of adverse events; dose reduction is recommended.
- CYP3A4 inducers (e.g., rifampicin, carbamazepine): May reduce efficacy by accelerating metabolism.
Patients should disclose all current medications, including over‑the‑counter products and herbal supplements, to avoid harmful interactions.
Practical Use: Dosing, Missed Dose, Overdose
- Standard starting dose: 50 mg taken as a single tablet, approximately 30–60 minutes before anticipated sexual activity.
- Dose titration: May be increased to 100 mg or decreased to 25 mg based on efficacy and tolerability. Do not exceed one tablet per 24‑hour period.
- Missed dose: Sildenafil is not a daily medication. If a dose is forgotten, take it only when sexual activity is planned; do not take a double dose to “make up” for the missed one.
- Overdose: Symptoms may include severe hypotension, dizziness, prolonged erection, or visual disturbances. Seek immediate medical attention; supportive care is the mainstay of treatment.
- Food and alcohol: A high‑fat meal can delay onset by up to 2 hours. Moderate alcohol intake is permissible, but excessive consumption may exacerbate hypotension and dizziness.
- Comorbidities: Patients with severe renal (creatinine clearance < 30 mL/min) or hepatic impairment should use a reduced dose (25 mg) and consult a clinician before initiation.
Buying Aurogra from Our Online Pharmacy
Aurogra can be purchased securely from our online pharmacy in the UK. We specialise in providing verified, high‑quality generic medications at prices close to the manufacturer’s cost. Our service includes:
- Affordable pricing: Transparent, near‑manufacturing‑cost rates that minimise out‑of‑pocket expense.
- Verified quality: All batches are sourced from licensed overseas suppliers that comply with GMP and EU/UK regulatory standards.
- Guaranteed delivery: Discreet, reliable shipping with express options (typically 7 days) and standard airmail (approximately 3 weeks).
- Pharmacy‑broker model: We act as an intermediary between customers and internationally licensed pharmacies, ensuring privacy and compliance with UK personal‑import regulations.
For patients who face limited access through local pharmacies or insurance schemes, this approach offers a safe, cost‑effective alternative to obtain Aurogra.
FAQ
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Is Aurogra available in both tablet and liquid formulations?
Aurogra is marketed only as an oral tablet. No liquid or chewable versions have been registered for this product in the UK. -
How should Aurogra be stored during summer travel?
Store the tablets in a cool, dry place away from direct sunlight and temperatures above 30 °C. If travelling abroad, keep the medication in a sealed container within your carry‑on luggage to avoid temperature extremes in checked baggage. -
What does the imprint on an Aurogra tablet look like?
Aurogra tablets typically bear a numeric imprint indicating the strength (e.g., “50” for 50 mg) along with the manufacturer’s logo. The exact design may vary between batches but is consistent with regulatory marking requirements. -
Can Aurogra be imported for personal use without a UK prescription?
Personal import of prescription‑only medicines is permitted under UK law provided the supply is for a private individual, the quantity does not exceed a three‑month supply, and the product is obtained from a licensed overseas pharmacy. -
Are there specific warnings for men of Asian ancestry?
Clinical data suggest that some Asian populations may experience higher plasma concentrations of sildenafil at standard doses. Dose adjustment to 25 mg is often recommended for initial therapy in these groups. -
Does Aurogra contain any allergens such as lactose or gluten?
In the UK formulation, the inactive ingredients include microcrystalline cellulose, magnesium stearate, and lactose. Patients with severe lactose intolerance should discuss alternatives with a healthcare professional. -
How does Aurogra compare with older ED drugs like vardenafil?
Sildenafil (Aurogra) and vardenafil share the same PDE5 inhibition mechanism but differ in pharmacokinetics. Sildenafil has a slightly longer half‑life, offering a wider “window of opportunity” (up to 12 hours), whereas vardenafil may have a quicker onset but a shorter duration. -
What is the history behind the development of sildenafil?
Sildenafil was first synthesized by Pfizer in the late 198s as a potential antihypertensive agent. Unexpectedly, its effect on penile erection was discovered during clinical trials, leading to its approval for ED in 1998. -
Will taking Aurogra affect routine blood tests or drug screening?
Sildenafil does not typically interfere with standard laboratory panels or most workplace drug screens. However, some specialized tests for phosphodiesterase inhibitors may detect the drug if specifically requested. -
Is it safe to use Aurogra in combination with recreational drugs such as poppers?
The use of nitrite inhalants (“poppers”) together with sildenafil can cause additive vasodilation, markedly increasing the risk of severe hypotension and fainting. This combination is strongly discouraged.
Glossary
- Phosphodiesterase‑5 (PDE5) inhibitor
- A class of drugs that block the enzyme PDE5, preventing breakdown of cGMP and thereby facilitating smooth‑muscle relaxation in the penis.
- Priapism
- A prolonged, painful erection lasting more than four hours, which can cause permanent tissue damage if not treated promptly.
- Bioavailability
- The proportion of an administered dose that reaches systemic circulation unchanged; sildenafil has an oral bioavailability of about 40 % due to first‑pass metabolism.
- Half‑life
- The time required for the plasma concentration of a drug to reduce by half; sildenafil’s half‑life is approximately four hours.
⚠️ Disclaimer
The information provided about Aurogra is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Aurogra for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.