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Cefixime is an oral cephalosporin antibiotic used to treat various bacterial infections, including respiratory, urinary, and ear infections. It works by stopping the growth of bacteria and is typically well tolerated.

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Generic Cefixime Information

Introduction

Cefixime is an oral antibacterial agent used to treat a range of community‑acquired infections in the United Kingdom. It belongs to the third‑generation cephalosporin class, offering broad‑spectrum activity against Gram‑negative and some Gram‑positive organisms. The active compound is Cefixime, marketed under various brand names such as Suprax. While the medication is primarily prescribed for bacterial infections, clinicians may also use it off‑label for certain resistant pathogens where culture data support its efficacy.

What is Cefixime?

Cefixime is the generic version of Suprax, containing the same active compound Cefixime. It is classified as a third‑generation cephalosporin antibacterial. The drug was developed in the early 199s and is now produced by several pharmaceutical companies worldwide, including Sandoz, Mylan, and Teva. Our online pharmacy provides this generic alternative as a cost‑effective treatment option, delivering the same therapeutic benefit as the branded product.

How Cefixime Works

Cefixime interferes with bacterial cell wall synthesis by binding to penicillin‑binding proteins (PBPs) located on the inner membrane of susceptible bacteria. This binding inhibits the cross‑linking of peptidoglycan strands, leading to weakened cell walls and eventual bacterial lysis. The drug is absorbed rapidly after oral administration, reaching peak plasma concentrations within 2–3 hours. It is eliminated primarily by renal excretion, with a half‑life of approximately 3–4 hours in adults with normal kidney function.

Conditions Treated with Cefixime

  • Uncomplicated urinary tract infections (UTIs) – Common in adult women; Cefixime covers many uropathogens such as E. coli and Klebsiella spp.
  • Acute uncomplicated gonorrhoea – Recommended when susceptibility testing confirms susceptibility; useful in settings where resistance to other agents is high.
  • Community‑acquired pneumonia (CAP) – Effective against Streptococcus pneumoniae and Haemophilus influenzae when atypical pathogens are excluded.
  • Pharyngitis/tonsillitis caused by Streptococcus spp. – Provides an oral alternative to parenteral therapy.
  • Otitis media – Useful for middle‑ear infections when the causative organism is susceptible.

In the UK, these infections represent a considerable burden on primary‑care services, and Cefixime offers a convenient oral regimen that reduces the need for hospital‑based intravenous therapy.

Who is Cefixime For?

Cefixime is appropriate for adult patients (≥18 years) with confirmed or strongly suspected infections caused by susceptible bacteria. Typical candidates include:

  • Individuals with uncomplicated UTIs who prefer oral therapy over intravaginal or intravenous options.
  • Sexually active adults diagnosed with gonorrhoea, especially when local antimicrobial‑resistance data support its use.
  • Patients with mild to moderate CAP who do not have risk factors for atypical pathogens or severe disease.

Cefixime is not recommended for patients with a known severe allergy to β‑lactam antibiotics, those with significant renal impairment (creatinine clearance < 30 mL/min) without dose adjustment, or pregnant women unless clearly indicated by a specialist. Pediatric use, while licensed in some regions, is outside the scope of this adult‑focused article.

Risks, Side Effects, and Interactions

Common

  • Gastrointestinal upset – nausea, diarrhoea, abdominal pain.
  • Headache – mild to moderate intensity, usually self‑limited.
  • Transient elevation of liver enzymes – mild ALT/AST rise without clinical consequence.

Rare

  • Stewart‑Graves syndrome – a reversible pseudomembranous colitis resembling C. difficile infection.
  • Cutaneous reactions – maculopapular rash or urticaria.
  • Altered taste (dysgeusia) – generally resolves after completion of therapy.

Serious

  • Anaphylaxis – rapid onset of wheeze, hypotension, or angioedema; requires immediate emergency treatment.
  • Severe hepatic injury – rare cases of jaundice and hepatitis reported.
  • Clostridioides difficile‑associated diarrhoea – may lead to severe colitis, especially after prolonged or repeated courses.
Drug–Drug Interactions
  • Probenecid – may increase Cefixime plasma concentrations by reducing renal excretion; dose adjustment may be necessary.
  • Warfarin – occasional reports of altered INR; monitor coagulation status during concurrent use.
  • Antacids containing aluminium or magnesium – can reduce oral absorption; separate administration by at least 2 hours.

Patients should disclose all concurrent medications, including over‑the‑counter products and supplements, to their healthcare provider before initiating Cefixime.

Practical Use: Dosing, Missed Dose, Overdose

  • Standard adult dose – 400 mg once daily for most infections; some indications (e.g., gonorrhoea) may use a single 800 mg dose.
  • Renal adjustment – for creatinine clearance 30–50 mL/min, reduce dose to 200 mg once daily; avoid use when clearance < 30 mL/min unless a specialist advises otherwise.
  • Missed dose – take the missed tablet as soon as remembered unless the next dose is due within 6 hours; in that case, skip the missed dose and continue the regular schedule. Do not double‑dose.
  • Overdose – symptoms may include nausea, vomiting, and diarrhoea. Seek medical attention promptly; supportive care and hydration are the mainstays of management.
  • Food and alcohol – Cefixime can be taken with or without food; high‑fat meals may slightly delay absorption but do not affect overall exposure. Alcohol does not interact directly, but excessive intake may worsen gastrointestinal side effects.
  • Comorbidities – patients with chronic liver disease should have liver function monitored, though dose adjustment is not routinely required.

Buying Cefixime from Our Online Pharmacy

Cefixime can be purchased from our online pharmacy in the UK. Our service delivers:

  • Affordable pricing – generic supply is sourced near manufacturer cost, offering savings compared with branded products.
  • Verified quality – all items are sourced from licensed overseas suppliers who meet EU Good Manufacturing Practice (GMP) standards.
  • Guaranteed delivery – discreet packaging with options for 7‑day express shipping or standard airmail (approximately 3 weeks).

We operate as a pharmacy broker service, partnering with overseas licensed pharmacies to provide a discreet, privacy‑focused solution for patients who lack convenient access to traditional pharmacies or insurance‑based prescription services. Our platform ensures secure transactions, reliable tracking, and a customer‑support team knowledgeable about international medication logistics.

FAQ

  • Is Cefixime available in both brand‑name and generic forms in the UK?
    Yes. The original brand‑name product is Suprax, while numerous generic manufacturers produce Cefixime tablets containing the same active ingredient. Generic versions are typically less expensive and widely accessible through online pharmacies.

  • What does a Cefixime tablet look like?
    Most generic tablets are white, film‑coated, and round or oval shaped, containing 400 mg of Cefixime. In addition to the active compound, they may include lactose, microcrystalline cellulose, and magnesium stearate as inactive ingredients.

  • Does Cefixime require refrigeration?
    No. Cefixime tablets are stable at room temperature (15‑30 °C). They should be stored in a dry place, protected from moisture and direct sunlight, and kept out of the bathroom where humidity can degrade the product.

  • Can I travel with Cefixime on an international flight?
    Yes, as long as you carry the medication in its original packaging with a clearly printed label. Some countries may ask for a prescription declaration; having a copy of your prescription or a doctor's note can facilitate customs clearance.

  • Are there differences in Cefixime formulations between the EU and other regions?
    The core active ingredient is identical worldwide, but excipients may vary. EU formulations often use lactose as a filler, whereas some Asian versions may contain alternative binders. These differences rarely affect efficacy but can be relevant for patients with specific allergies.

  • Is Cefixime safe for people with a penicillin allergy?
    While Cefixime is a β‑lactam, cross‑reactivity between cephalosporins and penicillins is low (approximately 1‑5 %). Patients with a history of severe IgE‑mediated penicillin allergy should discuss the risk with their clinician before starting Cefixime.

  • How does Cefixime compare with older cephalosporins such as cefuroxime?
    Cefixime offers broader Gram‑negative coverage and improved oral bioavailability, allowing once‑daily dosing. Cefuroxime, a second‑generation cephalosporin, requires twice‑daily dosing and has less activity against Enterobacter spp. The choice depends on the pathogen’s susceptibility profile.

  • What are the regulatory requirements for importing Cefixime into the UK for personal use?
    Personal import of a single‑patient supply of a licensed medication is permitted under UK law, provided the quantity does not exceed a three‑month supply and the product complies with UK standards. Importers must retain the original packaging and a copy of the prescription, if requested by customs.

  • Does Cefixime appear on standard drug testing panels?
    No. Cefixime is not a controlled substance and does not show up on routine occupational drug‑screening panels. However, some specialized assays could theoretically detect β‑lactam antibiotics, though this is uncommon.

  • Can Cefixime be taken with a high‑fiber diet?
    A high‑fiber diet does not interfere with Cefixime absorption. Nevertheless, fiber can sometimes cause gastrointestinal discomfort when combined with antibiotics; spacing the medication away from large meals may improve tolerability.

  • What is the environmental impact of Cefixime disposal?
    Like many pharmaceuticals, Cefixime residues can enter water systems if flushed down the drain. The recommended disposal method is to return unused tablets to a pharmacy take‑back scheme or follow local hazardous‑waste guidelines to minimise ecological contamination.

Glossary

Cephalosporin
A class of β‑lactam antibiotics derived from the fungus Acremonium. They work by disrupting bacterial cell wall synthesis.
Penicillin‑Binding Protein (PBP)
Enzymes located on the bacterial cell membrane that catalyse the cross‑linking of peptidoglycan strands; target of β‑lactam antibiotics.
Renal Clearance
The volume of plasma cleared of a drug by the kidneys per unit time, usually expressed in mL/min. It determines dose adjustments for drugs eliminated primarily by the kidneys.

⚠️ Disclaimer

The information provided about Cefixime is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Cefixime for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.

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