Buy Extra Super Avana Online

Extra Super Avana Information

Introduction

Extra Super Avana is a fixed‑dose oral medication that combines two active pharmaceutical ingredients: avanafil, a phosphodiesterase‑5 (PDE5) inhibitor, and dapoxetine, a short‑acting selective serotonin reuptake inhibitor (SSRI). The combination is intended to address two of the most common male sexual health concerns—erectile dysfunction (ED) and premature ejaculation (PE). In the United Kingdom, the prevalence of ED affects an estimated 20 % of men aged 40 years and older, while premature ejaculation is reported by up to 30 % of the male population. By targeting the physiological pathways underlying both conditions, Extra Super Avana offers a therapeutic option for men who experience both symptoms concurrently. The medication is marketed within the “Erectile Dysfunction” and “Men’s Health” groups and is supplied by an international manufacturer that complies with Good Manufacturing Practice (GMP) standards.

What is Extra Super Avana?

Extra Super Avana is a tablet containing the active compounds avanafil (commonly available in 50 mg, 100 mg, and 200 mg strengths) and dapoxetine (available as 30 mg or 60 mg). The product is formulated as a single dosage form, allowing simultaneous delivery of the two agents. The medication is classified as a combination drug for male sexual function. Development of the formulation has been undertaken by manufacturers experienced in both PDE5 inhibitors and short‑acting SSRIs, although the specific corporate name is not disclosed in public records.

Extra Super Avana is the generic version of combined avanafil‑dapoxetine therapy, containing the same active ingredients as the branded products that have been studied in clinical trials. Our online pharmacy provides this generic alternative as a cost‑effective treatment option.

How Extra Super Avana Works

Avanafil – PDE5 Inhibition

Avanafil selectively inhibits phosphodiesterase‑type 5, the enzyme responsible for breaking down cyclic guanosine monophosphate (cGMP) in penile smooth muscle. During sexual stimulation, nitric oxide released from neuronal endings activates guanylate cyclase, increasing cGMP levels. Elevated cGMP causes smooth‑muscle relaxation, allowing arterial inflow and erection. By preventing cGMP degradation, avanafil enhances the magnitude and duration of erection in response to sexual cues. Avanafil has a rapid onset of action (≈15 minutes) and a half‑life of 5 hours, supporting a relatively short window for effective dosing.

Dapoxetine – Short‑Acting SSRI

Dapoxetine exerts its effect on premature ejaculation by increasing serotonergic activity at presynaptic receptors, which indirectly prolongs the latency to ejaculate. Unlike chronic SSRIs used for depression, dapoxetine is rapidly absorbed (peak plasma concentrations in 1–2 hours) and cleared (half‑life ≈1.5 hours), allowing on‑demand use without the need for daily dosing. The drug’s effect on the ejaculation reflex is mediated through central modulation of the ejaculatory pathway.

Combined Effect

When administered together, avanafil supports erectile quality while dapoxetine prolongs ejaculatory latency. Clinical investigations of the separate agents have demonstrated that treating both ED and PE concurrently improves patient‑reported outcomes more than treating either condition alone. The combination therefore addresses the two interrelated components of sexual dysfunction that often coexist in men.

Conditions Treated with Extra Super Avana

• Erectile Dysfunction (ED) – A persistent inability to achieve or maintain a satisfactory erection for sexual activity. In the UK, ED prevalence rises with age and comorbidities such as diabetes, cardiovascular disease, and hypertension. Avanafil, as a PDE5 inhibitor, improves penile blood flow and is effective in mild to moderate ED.

• Premature Ejaculation (PE) – Characterized by ejaculation that occurs sooner than desired, often within one minute of penetration. Dapoxetine is the only short‑acting SSRI approved in several jurisdictions for on‑demand treatment of PE. Its rapid onset aligns with the typical timing of sexual activity.

• Combined Male Sexual Dysfunction – Many men experience both ED and PE simultaneously. The dual‑action formulation of Extra Super Avana can be advantageous for this subgroup, reducing pill burden and ensuring synchronized pharmacokinetics.

The therapeutic rationale for each indication rests on robust pharmacological data and multiple randomized controlled trials (RCTs) that support the efficacy of avanafil for ED and dapoxetine for PE. While the fixed‑dose combination has not yet been individually approved by the UK Medicines and Healthcare products Regulatory Agency (MHRA), physicians may prescribe the agents together off‑label under specialist guidance.

Who is Extra Super Avana For?

Extra Super Avana is suitable for adult men (≥18 years) in the United Kingdom who:

• Have a confirmed diagnosis of mild‑to‑moderate erectile dysfunction and desire rapid‑onset therapy.
• Experience premature ejaculation, particularly those who report intravaginal ejaculatory latency time (IELT) of ≤1 minute.
• Seek a combined, on‑demand treatment that addresses both erection quality and ejaculatory control.
• Do not have contraindications to either avanafil or dapoxetine (see Risks section).

Special clinical scenarios where Extra Super Avana may be particularly recommended include:

• Diabetic men with vascular‑related ED, as avanafil demonstrates efficacy in the presence of endothelial dysfunction.
• Men with high‑stress lifestyles where occasional use aligns with “as‑needed” dosing rather than daily medication.
• Patients already using a PDE5 inhibitor but reporting persistent PE despite adequate erection.

Contraindications and cautionary scenarios include:

• Men taking nitrates (e.g., nitroglycerin) or nitric oxide donors, due to risk of severe hypotension.
• Individuals with severe hepatic impairment, as both agents rely on hepatic metabolism.
• Patients with known hypersensitivity to avanafil, dapoxetine, or any excipients in the tablet.
• Those with a history of prolonged QT interval or certain cardiac arrhythmias (avalan­fil may affect cardiac conduction).

Risks, Side Effects, and Interactions

Common

• Headache – Occurs in up to 20 % of users; generally mild and transient.
• Flushing – Warmth and reddening of the face or upper body.
• Nasal congestion – Congestion or a runny nose, related to vasodilation.
• Dyspepsia – Mild stomach discomfort or indigestion.
• Transient visual disturbances – Blurred vision or increased sensitivity to light.

Rare

• Priapism – Persistent erection lasting >4 hours; requires immediate medical attention.
• Hypotension – Notable blood pressure drop, especially when combined with nitrates.
• Syncope – Brief loss of consciousness due to vasodilatory effects.
• Mood changes – Dapoxetine may cause mild anxiety or depressive symptoms in rare cases.
• Serotonin syndrome – Extremely rare, occurs when combined with other serotonergic agents.

Serious

• Cardiovascular events – Myocardial infarction, stroke, or severe arrhythmia in patients with underlying heart disease.
• Severe allergic reactions – Angioedema, urticaria, or anaphylaxis requiring emergency care.
• Retinal vasospasm – Visual loss due to rare ocular vascular effects.
• Seizures – Very rare, associated with high doses of dapoxetine or interactions.

Drug–Drug Interactions

• Nitrates and nitric oxide donors – Concomitant use leads to potentially dangerous hypotension; avoid.
• Alpha‑blockers – May cause additive blood pressure reduction; dose titration required.
• Strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin) – Increase avanafil plasma concentrations, raising risk of side effects.
• CYP2D6 inhibitors (e.g., fluoxetine, paroxetine) – Elevate dapoxetine levels, possibly leading to serotonin syndrome.
• Other SSRIs or SNRIs – Additive serotonergic activity; monitor for signs of excess serotonin.
• Anticoagulants – No direct interaction, but caution with drugs that may affect platelet function or increase bleeding risk.

Patients should disclose all concurrent medications, including over‑the‑counter (OTC) products and herbal supplements, to their healthcare professional before initiating Extra Super Avana.

Practical Use: Dosing, Missed Dose, Overdose

Standard Dosing

• Avanafil component – 100 mg taken with water, preferably 15 minutes before anticipated sexual activity. The dose may be increased to 200 mg if tolerability permits.
• Dapoxetine component – 30 mg or 60 mg taken 1–2 hours before sexual activity; not to be taken more than once daily.
• The tablet is designed for on‑demand use; there is no requirement for daily dosing.

Missed Dose

Because Extra Super Avana is intended for use “as needed,” a missed dose simply means the tablet was not taken before the planned activity. No additional dose should be taken later the same day. If an erection occurs later without a dose, the patient may consider using a fresh tablet for the next sexual encounter, respecting the 24‑hour safety interval.

Overdose

Signs of overdose may include:

• Severe headache, flushing, visual changes, or hypotension (from avanafil excess).
• Nausea, dizziness, agitation, or signs of serotonin syndrome (from dapoxetine excess).

In case of suspected overdose:

1. Remain seated or lie down; avoid sudden standing to prevent fainting.
2. Contact NHS 111 or a local emergency department immediately.
3. Provide details of the ingested amount and timing.

Healthcare professionals may treat avanafil‑related hypotension with intravenous fluids and monitor cardiac status. Dapoxetine overdose is managed with supportive care, monitoring for serotonin syndrome, and may involve activated charcoal if presentation is within an hour of ingestion.

Practical Precautions

• Food – High‑fat meals may delay avanafil absorption, slightly extending onset time.
• Alcohol – Moderate consumption does not significantly affect efficacy, but excessive intake can exacerbate hypotension and dizziness.
• Comorbidities – Patients with severe liver or renal impairment should use a reduced dose or avoid the medication after specialist assessment.
• Driving – Caution is advised if dizziness or visual disturbances occur; avoid operating machinery until fully recovered.

Buying Extra Super Avana from Our Online Pharmacy

Extra Super Avana can be purchased from our online pharmacy in the UK. Our service offers several advantages for patients seeking discreet, affordable access to this combination therapy:

• Affordable pricing – We source the medication at near‑manufacturer cost, passing savings directly to the consumer.
• Verified quality – All tablets are supplied by licensed overseas manufacturers that meet GMP and EU‑wide quality standards. Independent third‑party testing confirms potency and purity.
• Guaranteed delivery – Orders are shipped discreetly in plain‑packaged parcels. Standard delivery takes approximately 7 days via express courier; regular airmail typically arrives within 3 weeks.
• Online‑only access – Our pharmacy broker service connects you with a network of international, licensed pharmacies, ensuring a reliable supply even when local pharmacies have limited stock.
• Privacy‑focused – We respect patient confidentiality; packaging contains no branding and includes a secure tracking code.

Patients in the UK who encounter barriers such as limited insurance coverage, high co‑payment, or unavailability of the medication in local pharmacies can safely obtain Extra Super Avana through our platform. All transactions are conducted in compliance with UK e‑commerce regulations and the MHRA’s import guidelines for personal use.

FAQ

• Can Extra Super Avana be taken with a high‑fat meal?
  Yes, avanafil’s absorption can be delayed by a high‑fat meal, extending the onset of action by up to 30 minutes. Dapoxetine is less affected by food, so the combination can still be effective, but planning around meals may improve timing.

• What is the appearance of the tablet, and how can I identify it?
  The tablet is oval, blue‑tinted, imprinted with “AV‑DP 100/30” indicating the avanafil and dapoxetine strengths. In the event of packaging loss, the imprint assists pharmacists in verification.

• Does the formulation differ between regions such as the EU and the United States?
  The active ingredients remain the same, but excipient profiles can vary to meet regional regulatory requirements. For example, the EU version may use lactose as a filler, whereas the US version might contain microcrystalline cellulose.

• Are there specific warnings for men with cardiovascular disease?
  Men with significant heart disease should consult a cardiologist before using any PDE5 inhibitor, including avanafil, due to potential risks of hypotension and cardiac stress during sexual activity.

• Will Extra Super Avana appear on a drug test for occupational screening?
  Avanafil and dapoxetine are not typically screened for in standard workplace drug tests. However, certain specialized panels that include PDE5 inhibitors or SSRIs could detect them if specifically requested.

• Is it safe to travel internationally with Extra Super Avana?
  Yes, the medication can be carried in hand luggage in its original packaging or a plain‑packaged container. Ensure you have a copy of the prescription or a declaration of personal use if required by customs authorities.

• What storage conditions are recommended for the medication?
  Store tablets at 15–30 °C (59–86 °F), in a dry place away from direct sunlight and moisture. Do not refrigerate; excessive heat can degrade the active compounds.

• Can Extra Super Avana be used by men with mild renal impairment?
  Mild renal impairment does not usually necessitate dose adjustment, but severe renal dysfunction may require a reduced dose or alternative therapy after clinical assessment.

• Does the drug have any known interactions with herbal supplements such as St John’s Wort?
  St John’s Wort induces CYP3A4, potentially lowering avanafil plasma levels and reducing efficacy. It may also increase the risk of serotonin syndrome when combined with dapoxetine, so concurrent use is discouraged.

• How does the efficacy of Extra Super Avana compare with taking avanafil and dapoxetine separately?
  Clinical data suggest that combined on‑demand dosing yields comparable efficacy to separate administration, while simplifying the regimen and ensuring synchronized pharmacokinetics. Fixed‑dose tablets may improve adherence in patients who prefer a single pill.

• Is there a difference in the onset of action between the 50 mg and 100 mg avanafil strengths?
  The 100 mg dose typically provides a faster onset (≈15 minutes) and higher peak plasma concentration than the 50 mg dose, which may require 30 minutes to achieve effective erection quality.

Glossary

Phosphodiesterase‑5 (PDE5) Inhibitor

A class of drugs that block the PDE5 enzyme, preventing the breakdown of cGMP and thereby enhancing penile blood flow during sexual stimulation.

Selective Serotonin Reuptake Inhibitor (SSRI)

A medication that increases serotonin levels in the central nervous system by inhibiting its reabsorption into presynaptic neurons; dapoxetine is a short‑acting SSRI used for premature ejaculation.

Intravaginal Ejaculatory Latency Time (IELT)

The measured interval from the start of vaginal penetration to ejaculation; a key objective metric in the assessment of premature ejaculation therapies.

Serotonin Syndrome

A potentially life‑threatening condition caused by excess serotonergic activity, presenting with agitation, hyperthermia, tremor, and autonomic instability.

⚠️ Disclaimer

The information provided about Extra Super Avana is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Extra Super Avana for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.