Buy Generic Poxet Online

Generic Poxet Information

Introduction

Poxet is a prescription medication used primarily for the treatment of premature ejaculation (PE) in adult men. The product contains the selective serotonin re‑uptake inhibitor (SSRI) dapoxetine, which is classified within the men’s health therapeutic group. In the United Kingdom, dapoxetine is approved for on‑demand use to increase intravaginal ejaculatory latency time and improve sexual satisfaction for men who meet the clinical definition of PE. The drug is marketed in several countries under the brand name Priligy and is available as a generic formulation such as Poxet.

What is Poxet?

Poxet is a tablet formulation that delivers 30 mg or 60 mg of dapoxetine per dose. It is manufactured by [insert manufacturer if known; otherwise, the generic is supplied by licensed pharmaceutical partners]. The product is registered as a Selective Serotonin Re‑uptake Inhibitor (SSRI) specifically indicated for premature ejaculation. While the brand‑name version Priligy was the first dapoxetine product to receive European Medicines Agency (EMA) approval, Poxet provides the same active ingredient in a cost‑effective generic package.

How Poxet Works

Dapoxetine belongs to the SSRI class, but it differs from traditional SSRIs in its pharmacokinetic profile. After oral ingestion, dapoxetine is rapidly absorbed, reaching peak plasma concentrations within 1–2 hours. The drug inhibits the re‑uptake of serotonin (5‑HT) at presynaptic neuronal terminals, increasing extracellular serotonin levels in the central nervous system. Elevated serotonin activity in specific spinal and cerebral pathways delays the ejaculatory reflex, thereby extending the time to ejaculation. The short half‑life of dapoxetine (approximately 19 hours) permits single‑dose, on‑demand administration without the need for daily dosing, which distinguishes it from other SSRIs used for mood disorders.

Conditions Treated with Poxet

• Premature Ejaculation (PE) – The sole indication approved by the UK Medicines and Healthcare products Regulatory Agency (MHRA). PE is defined as ejaculation that occurs within one minute of vaginal penetration (primary PE) or a clinically significant reduction in latency time (secondary PE). Epidemiological surveys estimate that up to 30 % of UK men experience PE at some point in their lives, making effective treatment a public‑health priority.

Why the drug is effective: By enhancing serotonergic inhibition of the ejaculatory pathway, dapoxetine lengthens the intravaginal ejaculatory latency time (IELT) by an average of 2–3 minutes compared with placebo, as demonstrated in multiple double‑blind, randomized controlled trials (RCTs) conducted across Europe and North America.

No other therapeutic indications for Poxet are recognised in the UK at present.

Who is Poxet For?

• Men diagnosed with premature ejaculation who meet the clinical criteria of IELT ≤ 1 minute (primary) or a marked reduction in latency time (secondary).
• Adults aged 18 years and older who are in a stable sexual relationship and wish to improve sexual satisfaction for themselves or their partner.
• Patients who prefer on‑demand therapy rather than daily medication, as the short‑acting profile of dapoxetine suits occasional sexual activity.

Scenarios where Poxet is particularly recommended

• Men who have tried behavioral techniques (e.g., the “stop‑start” method) without satisfactory improvement.
• Individuals whose PE is associated with psychological distress, relationship strain, or reduced quality of life.

Contra‑indications and situations where caution is required

• Known hypersensitivity to dapoxetine or any tablet excipients.
• Current use of monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing an MAOI.
• Concomitant use of other serotonergic agents (e.g., tramadol, triptans) that could precipitate serotonin syndrome.
• Significant cardiovascular disease (e.g., uncontrolled hypertension, recent myocardial infarction) because dapoxetine may affect cardiac conduction.
• Severe hepatic impairment, as drug clearance is reduced.

Risks, Side Effects, and Interactions

Common

• Nausea
• Headache
• Dizziness
• Diarrhoea or constipation
• Dry mouth

These events are generally mild to moderate in intensity, appear within the first two hours after dosing, and resolve without medical intervention in most patients.

Rare

• Insomnia or abnormal dreams
• Blurred vision
• Increased sweating (hyperhidrosis)
• Palpitations without underlying cardiac disease

Rare side effects occur in < 1 % of users and should be reported to a healthcare professional if persistent.

Serious

• Serotonin syndrome – characterised by agitation, hyperthermia, tremor, hyperreflexia, and autonomic instability. Prompt medical attention is essential.
• Cardiac arrhythmias – especially in patients with pre‑existing conduction abnormalities or those taking other QT‑prolonging drugs.
• Severe allergic reactions – including angioedema, urticaria, or anaphylaxis.

Any occurrence of serious adverse events mandates immediate discontinuation of Poxet and emergency medical care.

Clinically relevant drug–drug interactions

• Monoamine oxidase inhibitors (MAOIs) – co‑administration is contraindicated.
• Tricyclic antidepressants (TCAs) and other SSRIs – increase risk of serotonin syndrome.
• PDE5 inhibitors (e.g., sildenafil, tadalafil) – combined use may enhance the risk of hypotension and dizziness; dose timing should be coordinated.
• CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine) – can raise dapoxetine plasma concentrations, potentially intensifying side effects.

Patients should provide a complete medication list, including over‑the‑counter and herbal products, before initiating therapy.

Practical Use: Dosing, Missed Dose, Overdose

• Standard dosing – The usual starting dose is 30 mg taken 1–3 hours before anticipated sexual activity. If tolerated, the dose may be increased to 60 mg on a subsequent occasion. Dapoxetine should not be taken more than once per day and not more than twice per week.
• Missed dose – If a dose is forgotten, it should be taken as soon as the need for sexual activity arises, provided that at least 1 hour remains before the next planned act. Do not take a double dose to “make up” for a missed tablet.
• Overdose – Symptoms may include severe nausea, vomiting, dizziness, seizures, or cardiac arrhythmia. In the event of suspected overdose, seek urgent medical assistance; supportive care and gastric decontamination are the mainstays of treatment.

Precautions

• Alcohol – Alcohol can potentiate dapoxetine‑related dizziness and should be limited.
• Food – A high‑fat meal may delay absorption and slightly reduce peak plasma levels; taking the tablet with a light snack is acceptable.
• Renal or hepatic impairment – Dose adjustment is not recommended; patients with severe impairment should avoid dapoxetine.

Buying Poxet from Our Online Pharmacy

Poxet can be obtained from our online pharmacy in the UK, which operates as a pharmacy‑broker service linking customers with licensed overseas suppliers.

• Affordable pricing – Generic dapoxetine is sourced close to manufacturer cost, offering a lower price point than many brand‑name equivalents.
• Verified quality – All batches are supplied by GMP‑certified manufacturers and undergo third‑party testing to confirm potency and purity.
• Guaranteed delivery – Discreet packaging is dispatched via express courier (typically 7 days) or standard airmail (approximately 3 weeks), with tracking available for each order.
• Online‑only access – The service enables patients who face limited availability in local pharmacies, or who prefer a private purchasing channel, to obtain Poxet safely and confidentially.

Our pharmacy adheres to UK import regulations for personal use, ensuring that each shipment complies with the MHRA’s guidelines for non‑prescription import of medicines for personal consumption.

FAQ

• Is Poxet approved for use in women?
  No, dapoxetine is licensed only for adult males with premature ejaculation. Clinical trials have not evaluated safety or efficacy in female populations.

• Can Poxet be taken with antihypertensive medication?
  Generally, dapoxetine does not have a direct interaction with most antihypertensives, but it may cause mild dizziness. Patients on blood‑pressure‑lowering drugs should monitor their response and avoid activities requiring full alertness until they know how they react.

• What should I do if I experience a severe headache after taking Poxet?
  A mild to moderate headache is common and often resolves spontaneously. If the headache is intense, persistent, or accompanied by visual disturbances, seek medical advice promptly as it may indicate a more serious adverse reaction.

• Does the tablet have any notable inactive ingredients?
  Poxet tablets typically contain lactose, magnesium stearate, and microcrystalline cellulose as excipients. Patients with lactose intolerance should consult a pharmacist, although the amount is usually minimal.

• Is it safe to travel internationally with Poxet?
  Yes, as long as the medication is kept in its original packaging, labelled with the generic name and dosage, and stored at room temperature. Carry a copy of the prescription or a doctor’s letter if required by customs authorities.

• How long can I store Poxet before it expires?
  The product retains full potency for up to 24 months from the date of manufacture, provided it is stored below 25 °C, away from moisture and direct sunlight. Expiry dates are printed on each blister pack.

• Can Poxet affect drug testing for employment?
  Dapoxetine is not a controlled substance and is not typically screened for in standard occupational drug tests. However, specialized tests could detect SSRIs, so disclose usage if relevant to the employer’s policy.

• Are there any known differences between European and Asian formulations of dapoxetine?
  The active ingredient and required dosage are identical across regions, but some Asian formulations may use different fillers or tablet colours. Regulatory agencies in each region approve the specific excipient list, ensuring comparable safety and efficacy.

• What clinical trials supported the approval of dapoxetine for premature ejaculation?
  Large‑scale, double‑blind RCTs such as the PRIDE and PRE‑MI studies enrolled thousands of men across Europe and North America, demonstrating statistically significant improvements in IELT and patient‑reported satisfaction versus placebo.

• Does taking Poxet require regular liver function monitoring?
  Routine liver monitoring is not mandated for dapoxetine, but patients with known hepatic disease should have baseline liver tests and be monitored periodically, as impaired metabolism could increase drug exposure.

Glossary

Selective Serotonin Re‑uptake Inhibitor (SSRI)

A class of drugs that block the re‑absorption of serotonin in the brain, thereby increasing its availability and influencing mood, pain perception, and, in the case of dapoxetine, ejaculatory control.

Intravaginal Ejaculatory Latency Time (IELT)

The interval measured from the start of vaginal penetration to ejaculation; a primary endpoint in clinical trials of premature ejaculation treatments.

Serotonin Syndrome

A potentially life‑threatening condition caused by excess serotonergic activity, characterised by hyperthermia, agitation, autonomic instability, and neuromuscular abnormalities.

Pharmacokinetic Half‑Life

The time required for the plasma concentration of a drug to reduce by 50 %; dapoxetine’s half‑life is approximately 19 hours, supporting its on‑demand dosing schedule.

⚠️ Disclaimer

The information provided about Poxet is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Poxet for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.