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  • Active ingredient: Lansoprazole
  • Medical form: Pill
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Prevacid is indicated to treat and prevent stomach and active duodenal ulcers in for short-term (for 4 weeks) treatment.

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Generic Prevacid Information

Introduction

Prevacid, known internationally by its active ingredient lansoprazole, belongs to the Gastro Health group of medicines. It is a proton‑pump inhibitor (PPI) that reduces gastric acid production, providing relief for a range of acid‑related disorders. In the United Kingdom, Prevacid is prescribed by clinicians and dispensed by pharmacies for conditions such as gastro‑oesophageal reflux disease (GORD), peptic ulcer disease and the prevention of non‑steroidal anti‑inflammatory drug (NSAID)‑induced ulcers. The drug is manufactured by Takeda Pharmaceuticals and is regulated by the UK Medicines and Healthcare products Regulatory Agency (MHRA).


What is Prevacid?

Prevacid is the generic version of the original brand Prevacid®, containing the same active compound lansoprazole. Other well‑known lansoprazole brand names include Lanzor, Lansox and Prevacid® in different markets. Our online pharmacy provides this generic alternative as a cost‑effective treatment option, delivering the same therapeutic effect at a price close to the manufacturer’s cost.

Lansoprazole is classified as a proton‑pump inhibitor. It was first approved for clinical use in the early 199s and has since become a staple in the management of acid‑related gastrointestinal diseases. In the UK, it is listed in the British National Formulary (BNF) and follows the same prescribing guidelines as the brand‑named product.


How Prevacid Works

Lansoprazole acts on the gastric parietal cell’s H⁺/K⁺‑ATPase enzyme, commonly called the “proton pump.” By forming a covalent disulfide bond with cysteine residues on the pump, lansoprazole irreversibly blocks the final step of acid secretion. This inhibition reduces both basal and stimulated gastric acid output for up to 24 hours after a single dose.

Key pharmacokinetic points:

  • Onset of action: Acid suppression begins within 1 hour of ingestion, reaching maximal effect after 2–4 hours.
  • Duration: The effect persists for about 24 hours, allowing once‑daily dosing for most indications.
  • Metabolism and clearance: Lansoprazole is metabolised primarily by hepatic CYP2C19 and CYP3A4 enzymes; its metabolites are eliminated renally. Genetic polymorphisms in CYP2C19 can affect plasma levels, which is why dose adjustments may be required in poor metabolizers.

The result is an increased gastric pH that promotes ulcer healing, reduces reflux symptoms, and protects the gastrointestinal lining from NSAID‑induced injury.


Conditions Treated with Prevacid

  • Gastro‑oesophageal reflux disease (GORD):
    Prevalence in the UK is estimated at 15‑20 % of the adult population. Acid suppression relieves heartburn, regurgitation and oesophagitis, improving quality of life and preventing complications such as Barrett’s oesophagus.

  • Erosive oesophagitis:
    Endoscopically confirmed mucosal erosion benefits from rapid acid control, allowing mucosal repair within weeks of therapy.

  • Peptic ulcer disease (duodenal and gastric ulcers):
    By maintaining a higher gastric pH, lansoprazole supports ulcer healing and reduces the risk of recurrence.

  • Helicobacter pylori eradication (as part of triple therapy):
    Lansoprazole enhances the efficacy of antibiotics by creating a less acidic environment, which improves bacterial susceptibility.

  • NSAID‑induced ulcer prophylaxis:
    Long‑term NSAID users, especially those over 60 years or with a history of ulcer disease, receive protective therapy to prevent gastrointestinal bleeding.

  • Zollinger‑Ellison syndrome (rare):
    Although uncommon, high‑dose lansoprazole can control the severe hyper‑acidity seen in this endocrine tumour.

Each indication is supported by NICE technology appraisal guidance (TA150) and the BNF, which recommend lansoprazole as first‑line PPI therapy for most acid‑related conditions.


Who is Prevacid For?

  • Adults with frequent heartburn or reflux symptoms that persist despite lifestyle modification.
  • Patients diagnosed with erosive oesophagitis confirmed by endoscopy.
  • Individuals with confirmed duodenal or gastric ulcers, especially when Helicobacter pylori infection is present.
  • Long‑term NSAID users who have risk factors for gastrointestinal bleeding (age > 60, prior ulcer, concurrent anticoagulant therapy).
  • Patients requiring H. pylori eradication regimens, where lansoprazole forms part of the triple‑therapy protocol.

Contraindications and cautions

  • Known hypersensitivity to lansoprazole or any excipients in the tablet.
  • Severe hepatic impairment (Child‑Pugh class C) – dose reduction or alternative therapy may be needed.
  • Pregnancy and lactation: Lansoprazole is classified as Category B; it should only be used when clearly indicated.

Patients with a history of Clostridioides difficile infection, osteoporosis, or low magnesium levels should discuss risks with a clinician before initiating therapy, as long‑term PPI use has been associated with these conditions in observational studies.


Risks, Side Effects, and Interactions

Common

  • Headache
  • Diarrhoea or constipation
  • Abdominal pain or flatulence
  • Nausea
  • Dry mouth

These events are usually mild, transient and resolve without the need for discontinuation.

Rare

  • Cutaneous reactions (rash, pruritus, photosensitivity)
  • Elevated liver enzymes (transient ALT/AST rise)
  • Hypomagnesemia (particularly with prolonged therapy > 12 months)

Patients experiencing unexplained skin eruptions or persistent gastrointestinal symptoms should seek medical advice.

Serious

  • Clostridioides difficile‑associated diarrhoea – PPIs may alter gut flora, increasing infection risk.
  • Severe allergic reactions (anaphylaxis, angio‑oedema) – immediate medical attention required.
  • Fracture risk – long‑term high‑dose use has been linked to reduced bone mineral density, especially in post‑menopausal women and older adults.

Drug‑drug interactions

  • Antiplatelet agents (e.g., clopidogrel): Lansoprazole can reduce the activation of clopidogrel, potentially diminishing antiplatelet effect. Consider alternative PPIs (e.g., pantoprazole) when dual therapy is required.
  • Antiretrovirals (e.g., atazanavir, nelfinavir): Reduced plasma concentrations may occur, compromising HIV therapy.
  • Warfarin: Enhanced anticoagulant effect has been reported; monitor INR more closely.
  • Ketoconazole, Itraconazole, Voriconazole: Absorption of these antifungals is pH‑dependent; co‑administration may decrease their efficacy.

Patients should provide a full medication list, including over‑the‑counter drugs and herbal supplements, to avoid adverse interactions.


Practical Use: Dosing, Missed Dose, Overdose

  • Standard adult dosing (tablet form, oral):

    • GORD, erosive oesophagitis, ulcer prophylaxis: 30 mg once daily.
    • H. pylori eradication (triple therapy): 30 mg twice daily for 7–14 days.
    • Zollinger‑Ellison syndrome: 60 mg once daily, may be increased up to 90 mg based on acid output measurements.
  • Administration: Swallow whole with a glass of water, preferably 30 minutes before a meal. Food does not significantly affect absorption, but taking on an empty stomach enhances onset.

  • Missed dose: Take the missed tablet as soon as remembered unless it is near the time of the next scheduled dose. In that case, skip the missed tablet and continue with the regular schedule; do not double dose.

  • Overdose: Acute overdose of lansoprazole is unlikely to be life‑threatening. Symptoms may include mild nausea, vomiting or dizziness. Seek urgent medical assessment if large amounts are taken accidentally.

  • Precautions: Chronic alcohol intake may exacerbate gastritis; limit consumption while on therapy. Renal impairment does not require dose adjustment, but hepatic dysfunction may.


Buying Prevacid from Our Online Pharmacy

Prevacid can be purchased safely from our online pharmacy in the UK. Our service offers several advantages for patients seeking reliable access to generic lansoprazole:

  • Cost‑effective pricing: We source the medication near the manufacturer’s cost, passing savings directly to you.
  • Verified quality: All products are obtained from licensed overseas suppliers that comply with EU‑GMP standards, ensuring batch‑to‑batch consistency.
  • Guaranteed delivery: Discreet packaging is shipped via express delivery (typically 7 days) or regular airmail (~3 weeks), with tracking available for every order.
  • Online‑only accessibility: For individuals who encounter difficulties obtaining PPIs through local pharmacies or who reside in areas with limited stock, we provide a convenient digital route.

Our platform operates as a pharmacy broker service, partnering with internationally accredited pharmacies to bring medication to the UK market while respecting patient privacy. All orders are handled by qualified pharmacists who verify product authenticity before dispatch.


FAQ

  • Is Prevacid available in both brand‑name and generic forms in the UK?
    Yes. The original brand‑name product is marketed as Prevacid®, while generic lansoprazole tablets contain the identical active ingredient and are typically priced lower.

  • Does Prevacid require refrigeration?
    No. The tablets should be stored at controlled room temperature, between 15 °C and 30 °C, away from excess moisture and direct sunlight.

  • What does the Prevacid tablet look like?
    Generic lansoprazole tablets are usually white, round, and film‑coated, bearing the imprint “30 mg” or the manufacturer’s logo. Appearance may vary slightly between licensed suppliers.

  • Can I travel internationally with Prevacid?
    Yes, provided you keep the medication in its original packaging, carry a copy of the prescription or a pharmacist’s proof of purchase, and adhere to the destination country’s import regulations for personal use.

  • Are there any known differences between European and non‑European of lansoprazole?
    The active ingredient and dosage strength are the same, but excipients such as colourants or binders may differ to meet regional regulatory requirements. These variations rarely affect clinical efficacy.

  • What are the potential effects of taking Prevacid while breastfeeding?
    Limited data suggest that minimal amounts of lansoprazole are excreted in breast milk. It is generally considered compatible with breastfeeding, but mothers should discuss any concerns with a healthcare professional.

  • Is it safe to use Prevacid together with calcium or iron supplements?
    PPIs can reduce the absorption of certain minerals. To optimise absorption, take calcium or iron supplements at least two hours apart from the Prevacid dose.

  • How long can I store Prevacid before it expires?
    The typical shelf‑life is two to three years from the date of manufacture. Always check the expiry date printed on the pack before use.

  • Can Prevacid be imported for personal use without a UK licence?
    Personal import of a three‑month supply for a valid therapeutic need is permitted under UK law, provided the product is for personal use and not for resale.

  • Are there any specific warnings for Asian patients taking Prevacid?
    Asian populations have a higher prevalence of CYP2C19 poor‑metaboliser genotypes, which may lead to higher plasma concentrations of lansoprazole. Dose adjustment is rarely required, but clinicians may monitor therapeutic response more closely.


Glossary

Proton‑pump inhibitor (PPI)
A class of medication that irreversibly blocks the H⁺/K⁺‑ATPase enzyme in gastric parietal cells, reducing stomach acid secretion.
CYP2C19
A liver enzyme that metabolises many drugs, including lansoprazole. Genetic variations can affect drug levels and therapeutic response.
Helicobacter pylori
A spiral‑shaped bacterium that colonises the stomach lining, contributing to ulcer formation and gastric cancer risk. Eradication often requires a combination of antibiotics and a PPI.
Clostridioides difficile
A bacterium that can cause severe colitis, especially after disruption of normal gut flora by antibiotics or PPIs.

⚠️ Disclaimer

The information provided about Prevacid is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Prevacid for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.

Alternative names or trademarks of Generic Prevacid

Prevacid may be marketed under different names in various countries. All of them contain Lansoprazole as main ingredient. Some of them are the following:

Lansoprazole, Bamalite, Limpidex, Opiren, Takepron, Zoton, Lanzopral, Mesactol, Agopton, Lansobene, Dakar, Anzoprol, Lanogastro, Lanz, Ogastro, Fudermex, Gastride, Unival, Chexid, Razolager, Zomel, Palatrin, Pranix, Uldapril, Pylison, Lansolek, Lanzostad, Gastroliber, Lanzul, Lanzogastro, Lizul, Monolitum, Ogasto, Pampe, Acrilans, Ulcertec, Vogast, Biolanz

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