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Silagra Information
Introduction
Silagra is a tablet formulation that contains the active compound sildenafil. It belongs to the therapeutic group for erectile dysfunction (ED) and broader men’s‑health concerns. In the United Kingdom, sildenafil is prescribed to improve erectile function in men for whom physiological factors limit sexual performance. Although its primary indication is ED, sildenafil also has recognised secondary uses, most notably the treatment of pulmonary arterial hypertension under separate brand formulations. Silagra provides a cost‑effective, generic alternative to the original brand‑name product, Viagra, while delivering the same pharmacological effect.
What is Silagra?
Silagra is the generic version of Viagra®, containing the same active ingredient, sildenafil citrate. It is manufactured by a range of licensed pharmaceutical companies that hold marketing authorisation from the UK Medicines and Healthcare products Regulatory Agency (MHRA). As a generic, Silagra is required to meet the same standards of quality, safety, and efficacy as the brand‑name product.
“Silagra is the generic version of Viagra, containing the same active compound sildenafil. Our online pharmacy provides this generic alternative as a cost‑effective treatment option.”
Silagra is supplied as a solid oral tablet, typically in 25 mg, 50 mg and 100 mg strengths, and is intended for adult male patients with diagnosed erectile dysfunction.
How Silagra Works
Sildenafil belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors. During sexual stimulation, nitric oxide is released in the corpus cavernosum of the penis, activating guanylate cyclase and increasing cyclic guanosine monophosphate (cGMP). cGMP relaxes smooth muscle and allows arterial inflow, producing an erection. PDE5 is the enzyme that degrades cGMP. By selectively inhibiting PDE5, sildenafil sustains higher cGMP levels, prolonging smooth‑muscle relaxation and facilitating erection in response to sexual arousal.
Key pharmacokinetic points:
- Onset of action: typically 30–60 minutes after oral intake.
- Peak plasma concentration: reached in about 1 hour.
- Duration of effect: 4–6 hours, with some benefit up to 12 hours in certain individuals.
- Elimination: primarily hepatic metabolism via CYP3A4, with a terminal half‑life of approximately 4 hours.
These properties explain why the medication is taken “as needed” rather than on a fixed schedule.
Conditions Treated with Silagra
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Erectile Dysfunction (ED): The principal approved indication in the UK. ED affects an estimated 10 % of men aged 40–49 and rises to 30 % in those over 70, according to NHS data. Sildenafil improves the ability to achieve and maintain an erection sufficient for sexual activity.
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Pulmonary Arterial Hypertension (PAH) – off‑label: Sildenafil’s vasodilatory effect on pulmonary vessels is the basis for its use in PAH under distinct brand names (e.g., Revatio®). While Silagra is not marketed for PAH in the UK, the pharmacological rationale is shared.
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Secondary sexual dysfunction associated with certain medical conditions: In men with diabetes, post‑prostate‑surgery status, or spinal cord injury, sildenafil has demonstrated efficacy in controlled trials, supporting its inclusion in treatment algorithms for these sub‑populations.
Silagra’s effectiveness in each of these contexts derives from the same PDE5‑inhibition mechanism, which enhances nitric‑oxide‑mediated vasodilation where required.
Who is Silagra For?
Silagra is for adult men who have been assessed and diagnosed with erectile dysfunction and for whom a PDE5‑inhibitor is deemed suitable. Typical candidates include:
- Men with vascular or neurogenic causes of ED, such as diabetes‑related endothelial dysfunction, atherosclerosis, or nerve injury after pelvic surgery.
- Individuals who respond poorly to lifestyle measures alone (e.g., exercise, smoking cessation).
- Patients whose psychogenic components are present but who also have a physiological limitation that can be pharmacologically addressed.
Silagra is not recommended for:
- Men taking nitrates (e.g., nitroglycerin) or nitric‑oxide donors, due to the risk of profound hypotension.
- Patients with severe uncontrolled hypertension or recent myocardial infarction without cardiology clearance.
- Individuals with a known hypersensitivity to sildenafil or any tablet excipients.
- Women and children, as the drug has not been evaluated for these groups.
A thorough medical review—including cardiovascular assessment—is essential before initiating therapy.
Risks, Side Effects, and Interactions
Common
- Headache
- Flushing (warmth, redness of the face or neck)
- Dyspepsia or indigestion
- Nasal congestion
- Visual disturbances (blurred vision, a blue‑tinted view)
These effects are usually mild, transient, and resolve without intervention.
Rare
- Priapism (prolonged erection lasting > 4 hours) – requires urgent medical attention.
- Sudden hearing loss or decreased hearing.
- Severe hypotension, especially when combined with vasodilators.
Serious
- Cardiovascular events such as myocardial infarction or stroke are exceedingly rare but may occur in patients with pre‑existing disease.
- Vision loss due to non‑arteritic anterior ischemic optic neuropathy (NAION).
If any serious symptom emerges, discontinue Silagra and seek emergency care.
Drug–Drug Interactions
- Nitrates (e.g., glyceryl trinitrate, isosorbide dinitrate) – contraindicated.
- Alpha‑blockers (e.g., tamsulosin, alfuzosin) – may cause additive blood‑pressure lowering; dose adjustment and timing considerations are required.
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) – increase sildenafil plasma levels; consider a reduced starting dose (25 mg).
- CYP3A4 inducers (e.g., rifampicin, carbamazepine) – may reduce efficacy; monitor response.
Patients should inform healthcare providers of all concomitant medications, including over‑the‑counter products and herbal supplements.
Practical Use: Dosing, Missed Dose, Overdose
- Standard starting dose: 50 mg taken as a single tablet about one hour before sexual activity.
- Dose adjustment: Based on efficacy and tolerability, the dose may be increased to 100 mg or decreased to 25 mg. The maximum recommended frequency is once per 24‑hour period.
- Food considerations: A high‑fat meal can delay absorption and reduce peak concentration; taking the tablet on an empty stomach may result in a quicker onset.
- Alcohol: Moderate consumption generally does not alter efficacy, but excessive alcohol can impair erection and increase the risk of hypotension.
Missed dose: Silagra is taken only when sexual activity is anticipated. If a dose is forgotten, simply skip it and resume the usual “as‑needed” schedule; do not double‑dose.
Overdose: Signs may include severe hypotension, dizziness, prolonged erection, or cardiac symptoms. If overdose is suspected, seek immediate medical attention; supportive care and blood‑pressure monitoring are the mainstays of treatment.
Buying Silagra from Our Online Pharmacy
Silagra can be obtained safely and discreetly from our online pharmacy in the UK. The service offers several advantages for patients seeking an affordable generic option:
- Near‑manufacturer pricing: By sourcing directly from licensed overseas manufacturers, we keep costs close to the wholesale level, delivering significant savings compared with many high‑street pharmacies.
- Verified quality: All batches are manufactured under Good Manufacturing Practice (GMP) standards and are inspected by independent quality‑control laboratories before dispatch.
- Guaranteed delivery: Options include express shipping (delivery within 7 days) and standard airmail (approximately 3 weeks). All packages are sealed, unmarked, and sent in discreet packaging to protect privacy.
- Pharmacy‑broker model: We act as a broker, partnering with accredited international pharmacies that hold proper licences. This model enables us to provide medications that may be unavailable or expensive through conventional UK channels while still complying with import regulations for personal use.
Patients who face limited access to conventional pharmacies, restrictive insurance formularies, or who simply desire a cost‑effective alternative can benefit from this streamlined, privacy‑focused approach.
FAQ
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Is Silagra available in both brand‑name and generic forms in the UK?
Yes. The original brand‑name product is Viagra®, produced by Pfizer. Silagra is the generic counterpart, containing the identical active ingredient sildenafil and offering a lower price point. -
How should Silagra be stored to maintain its potency?
Store tablets at a controlled room temperature between 15 °C and 30 °C (59 °F–86 °F). Keep the medication in its original blister pack, away from direct sunlight, moisture, and heat sources such as radiators. -
Can I travel internationally with Silagra tablets?
Yes, provided the medication is for personal use and the quantity does not exceed a 30‑day supply. Carry the prescription (or a doctor’s letter if required) and keep the tablets in their original packaging to facilitate customs inspection. -
Do different regions manufacture Silagra with varying inactive ingredients?
Minor formulation differences can exist between manufacturers, such as variations in filler or binder compounds. However, all licensed versions must meet MHRA bioequivalence standards, ensuring comparable efficacy and safety. -
What are the most common visual side effects, and are they reversible?
Patients may notice a blue‑tinted colour perception, increased light sensitivity, or blurred vision. These effects are usually transient, resolving within a few hours as plasma sildenafil levels decline. Persistent visual disturbances should be reported to a healthcare professional. -
Is there a risk of a positive result on drug–screening tests after taking Silagra?
Standard workplace drug screens do not test for sildenafil. However, specialized toxicology panels could detect the compound if specifically requested. Routine testing for ED medications is uncommon. -
Can Silagra be used in men with benign prostatic hyperplasia (BPH)?
Sildenafil has no direct therapeutic effect on BPH symptoms and is not indicated for that purpose. It can be safely co‑prescribed with BPH medications (e.g., alpha‑blockers) if dose timing is managed to avoid additive blood‑pressure effects. -
Why is a low‑fat meal sometimes recommended with Silagra?
A high‑fat meal can delay the absorption of sildenafil, postponing the onset of action by up to 2 hours. Consuming a low‑fat or moderate‑carbohydrate meal reduces this delay, allowing the drug to work closer to the typical 30–60 minute window. -
Are there any known differences in efficacy between the 25 mg and 50 mg strengths?
Clinical trials show a dose‑response relationship: 50 mg provides greater improvement in erection rigidity for most men compared with 25 mg, while still maintaining a comparable safety profile. The lower dose is useful for patients who are sensitive to side effects or who are taking interacting medications. -
What should I do if I experience a prolonged erection lasting more than four hours?
A prolonged erection (priapism) is a medical emergency. Seek immediate care at an emergency department or call emergency services. Prompt treatment reduces the risk of permanent tissue damage. -
Does the generic version contain any allergens such as lactose or gluten?
In the United Kingdom, most Silagra tablets are formulated without lactose or gluten, but excipient lists can vary between manufacturers. Patients with known dietary allergies should review the specific product’s ingredient list before use. -
How does the cost of Silagra compare with the brand‑name Viagra in the UK market?
Generic sildenafil typically costs 30–70 % less per tablet than the branded product, depending on the strength and retailer. Our online pharmacy aims to offer prices close to the wholesale cost, providing additional savings for patients.
Glossary
- Sildenafil
- A selective phosphodiesterase type 5 (PDE5) inhibitor that enhances cGMP‑mediated smooth‑muscle relaxation in the penis, facilitating erection.
- Phosphodiesterase type 5 (PDE5) inhibitor
- A class of drugs that block the enzyme PDE5, preventing the breakdown of cyclic guanosine monophosphate (cGMP) and thereby prolonging vasodilation.
- Erectile Dysfunction (ED)
- The persistent inability to achieve or sustain an erection sufficient for satisfactory sexual performance, affecting physical, psychological, or mixed origins.
- Therapeutic Window
- The dosage range within which a medication produces the desired therapeutic effect without causing unacceptable side effects.
⚠️ Disclaimer
The information provided about Silagra is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Silagra for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.