Buy Generic Theo-24 Cr Online

Generic Theo-24 Cr Information

Introduction

Theo-24 Cr is a oral bronchodilator that contains the methylxanthine theophylline. It belongs to the asthma medication group and is used primarily to improve breathing in adults with chronic obstructive pulmonary disease (COPD) or asthma that is not adequately controlled by inhaled therapy alone. The product is marketed in the United Kingdom by an international manufacturer that supplies medicines to licensed overseas pharmacies. In addition to its role in asthma, theophylline has limited evidence for use in other obstructive airway conditions, such as acute‐exacerbations of COPD, where it may act as an adjunct to standard treatment.

What is Theo-24 Cr?

Theo-24 Cr is the generic version of Theochin (a well‑known brand of theophylline tablets), containing the same active compound theophylline. Our online pharmacy provides this generic alternative as a cost‑effective treatment option. The medication is classified as a methyl‑xanthine bronchodilator and is listed under the UK Medicines and Healthcare products Regulatory Agency (MHRA) as a standard medicinal product for adult use.

How Theo‑24 Cr Works

Theophylline exerts its therapeutic effect through several complementary mechanisms:

• Phosphodiesterase inhibition – By blocking the enzyme PDE‑4, theophylline raises intracellular cyclic adenosine monophosphate (cAMP) levels, leading to relaxation of smooth muscle in the bronchial tree.
• Adrenoceptor antagonism – The drug sensitises β₂‑adrenergic receptors, enhancing the response to endogenous catecholamines and improving bronchodilation.
• Anti‑inflammatory activity – At therapeutic concentrations, theophylline suppresses the release of pro‑inflammatory cytokines (e.g., interleukin‑6, tumour necrosis factor‑α) from airway immune cells, contributing to reduced airway hyper‑responsiveness.

Therapeutic concentrations are achieved within 1–3 hours after a standard oral dose and are maintained for 6–12 hours, reflecting a half‑life of approximately 8 hours in most adults. Renal clearance is the predominant elimination pathway; therefore, kidney function and interacting drugs that modify renal excretion significantly influence plasma levels.

Conditions Treated with Theo‑24 Cr

Asthma (moderate to severe) – Theophylline is used as an add‑on therapy when inhaled corticosteroids and long‑acting β₂‑agonists fail to achieve optimal control (British Thoracic Society 2023). Its bronchodilator and anti‑inflammatory properties reduce symptom scores and the need for oral steroids.

Chronic obstructive pulmonary disease (COPD) – In stable COPD, theophylline improves lung function (FEV₁) and reduces exacerbation frequency, particularly when combined with inhaled bronchodilators (National Institute for Health and Care Excellence NICE guideline 2022).

Acute severe asthma attacks – When rapid bronchodilation is required and inhaled therapy is insufficient, oral theophylline may be administered under close monitoring to complement nebulised short‑acting β₂‑agonists.

In the UK, asthma affects approximately 5 % of adults (≈2.8 million) and COPD 2 % of the over‑65 population, underscoring the clinical relevance of a readily available, inexpensive bronchodilator such as Theo‑24 Cr.

Patient Populations Most Likely to Benefit

• Adults with persistent asthma whose disease remains uncontrolled despite maximal inhaled therapy. Theophylline is particularly valuable for patients who experience frequent night‑time wheeze or exercise‑induced bronchoconstriction.
• COPD patients with moderate to severe airflow limitation who have a high exacerbation risk score (>2 events/year) and require an additional oral bronchodilator to maintain stable lung function.
• Individuals with limited access to brand‑name inhalers owing to cost, availability, or prescribing restrictions. The generic cost‑advantage of Theo‑24 Cr can improve adherence.
• Patients on polypharmacy where theophylline’s anti‑inflammatory effect complements other agents, provided there are no contraindicating drug interactions (e.g., macrolide antibiotics, certain antifungals).

Contra‑indications include known hypersensitivity to methyl‑xanthines, severe uncontrolled cardiac disease (e.g., arrhythmia), and active seizure disorders. Use in pregnancy is reserved for specialist consultation because limited safety data exist.

Risks, Side Effects, and Interactions

Common adverse events

• Nausea, vomiting, or dyspepsia (10–15 % of users).
• Insomnia or restlessness, particularly at higher plasma concentrations.
• Mild tremor or headache.

Rare adverse events

• Urinary incontinence (≤1 % of patients).
• Elevated transaminases (liver enzyme rise) without clinical hepatitis.

Serious adverse events

• Seizures – dose‑related, especially in overdose or with interacting drugs that decrease clearance.
• Cardiac arrhythmias – ventricular tachycardia or atrial fibrillation in patients with underlying cardiac disease.
• Life‑threatening hypotension – rare but reported in cases of severe overdose.

Clinically relevant drug–drug interactions

• CYP1A2 inhibitors (e.g., ciprofloxacin, fluvoxamine, allopurinol) markedly raise theophylline levels and can precipitate toxicity.
• CYP1A2 inducers (e.g., smoking, carbamazepine, rifampicin) increase clearance, potentially reducing efficacy.
• Beta‑blockers may blunt β₂‑agonist response, necessitating careful monitoring of bronchoconstriction.
• Warfarin – theophylline can increase INR; dosage of anticoagulants may need adjustment.
• Macrolide antibiotics (e.g., erythromycin) and quinolones (e.g., enoxacin) reduce clearance, heightening risk of adverse reactions.

Patients should disclose all current medications, herbal products, and over‑the‑counter drugs to their prescriber before initiating Theo‑24 Cr.

Practical Use: Dosing, Missed Dose, Overdose

Standard dosing – Adults are commonly started on 200 mg three times daily (total 600 mg/day). Dose is titrated to achieve a therapeutic serum concentration of 10–20 µg·mL⁻¹, measured when possible. Dose adjustment is required for:

• Renal impairment – reduce by 25–50 % when creatinine clearance falls below 30 mL/min.
• Age > 65 years – lower initial dose (150 mg twice daily) due to reduced clearance.

Missed dose – If a dose is missed and the next scheduled dose is more than 6 hours away, the patient should take the missed tablet immediately, then resume the regular schedule. Doubling the dose to compensate is unsafe and may provoke toxicity.

Overdose – Ingestion of ≥ 5 g (approximately 50 tablets of 200 mg) is potentially life‑threatening. Immediate steps:

1. Contact emergency services (999) and inform them of a theophylline overdose.
2. Seek urgent medical care; activated charcoal may be administered if presentation is early.
3. Serum theophylline level should be measured; if > 30 µg·mL⁻¹, supportive care and possible sodium bicarbonate infusion are recommended.

Precautions – Theophylline is metabolised by the liver and excreted by the kidneys; patients should avoid excessive alcohol, which may increase CNS toxicity, and avoid smoking cessation without a dose reduction, as the loss of tobacco‑induced enzyme induction can double plasma concentrations within days.

Buying Theo‑24 Cr from Our Online Pharmacy

Theo‑24 Cr can be purchased from our online pharmacy in the UK. The service offers several advantages for adult patients seeking reliable access to this bronchodilator:

• Affordable pricing – The product is supplied at near‑manufacturer cost, making it markedly cheaper than many branded inhalers.
• Verified quality – All batches are sourced from licensed overseas suppliers that meet MHRA and European Pharmacopoeia standards.
• Guaranteed delivery – Discreet, tracked shipping with express options (7 days) or regular airmail (≈ 3 weeks) ensures receipt without interruption to therapy.
• Pharmacy‑broker model – We act as a broker, linking patients to overseas licensed pharmacies while preserving privacy and respecting data‑protection regulations.
• Regulatory compliance – The medication is shipped with full customs documentation, permitting personal import for non‑commercial use under the UK’s “self‑supply” provisions.

For patients with limited pharmacy access, insurance constraints, or cost concerns, purchasing Theo‑24 Cr through our online platform provides a safe, confidential route to an essential asthma medication.

FAQ

• **Is Theo‑24 Cr available in both brand‑name and generic forms in the UK?
  Yes. The original branded product is marketed as Theochin (a well‑known theophylline tablet), while Theo‑24 Cr is the generic version sold by our pharmacy. Both contain the same active ingredient and dosage strength, but the generic is generally less expensive.

• **What is the recommended storage condition for Theo‑24 Cr?
  The tablets should be kept at a controlled room temperature (15 °C–30 °C), protected from moisture, direct light, and heat. A dry, airtight container is ideal; do not store in humid environments such as a bathroom.

• **Does Theo‑24 Cr require refrigeration?
  No refrigeration is necessary. Theophylline is chemically stable at ambient temperature and does not require cold storage.

• **Can I travel internationally with Theo‑24 Cr tablets?
  Yes. Carry the medication in your hand luggage and keep the original packaging and a copy of the prescription or pharmacy invoice. Check the destination country’s import regulations for personal use of medication.

• **Are there any excipients in Theo‑24 Cr that might cause allergic reactions?
  Common inactive ingredients include lactose monohydrate, cellulose micro‑crystalline, and magnesium stearate. Patients with known hypersensitivity to these substances should consult a pharmacist before use.

• **How does Theo‑24 Cr differ from other methyl‑xanthine preparations like aminophylline?
  Theophylline (Theo‑24 Cr) is the pure active base, whereas aminophylline is a compound of theophylline and ethylenediamine used for intravenous administration. Both share the same mechanism but differ in formulation, route, and dosing.

• **What are the UK legal limits for personal import of medications like Theo‑24 Cr?
  Under the UK “personal import” scheme, an individual may import up to a three‑month supply for personal use without a licence, provided the product is for personal consumption and not for resale.

• **Will taking Theo‑24 Cr affect my results on a drug test for work?
  Theophylline is not a controlled substance and is not screened for in standard occupational drug‑testing panels. However, high plasma concentrations may be detectable in specialized toxicology screens.

• **Is there any difference in formulation of Theo‑24 Cr between the EU and Asian markets?
  The tablet formulation (200 mg) is consistent across regions, but some manufacturers may use different binders or colourants to meet local pharmacopeial requirements. Our supply follows the Europe‑wide standard formulation.

• **How long does it take for a new prescription of Theo‑24 Cr to reach the UK after ordering?
  With express shipping the tablet arrives within 7 working days; standard airmail delivery typically requires around 3 weeks. All shipments include a tracking number for patient monitoring.

Glossary

Bronchodilator – A medication that relaxes the muscles of the airways, increasing airflow to the lungs.

Therapeutic window – The concentration range of a drug in the blood that provides effective treatment with an acceptable safety margin.

CYP1A2 – A liver enzyme that metabolises theophylline; substances that inhibit or induce CYP1A2 can alter theophylline levels.

Half‑life – The time required for the plasma concentration of a drug to decrease by 50 %; for theophylline this is roughly 8 hours in healthy adults.

⚠️ Disclaimer

The information provided about Theo‑24 Cr is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Theo‑24 Cr for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.