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Generic Voltarol Information
Introduction
Voltarol is a non‑steroidal anti‑inflammatory drug (NSAID) that contains the active compound diclofenac. It is classified within the pain‑relief medication group and is widely used in the United Kingdom for the short‑term management of mild to moderate pain and inflammation. The product is commonly supplied in tablet, gel and topical patch forms, and is indicated for conditions such as osteoarthritis, rheumatoid arthritis, musculoskeletal injuries and postoperative pain. Though the brand name may differ across manufacturers, the therapeutic principle remains the inhibition of cyclo‑oxygenase enzymes, which reduces prostaglandin synthesis and thereby diminishes pain and swelling.
What is Voltarol?
- Voltarol is a commercial name for a diclofenac‑containing NSAID.
- Classification: non‑steroidal anti‑inflammatory drug, analgesic.
- Development: diclofenac was first synthesized in the 196s and introduced to the market as a systemic NSAID; formulations such as tablets, gels and patches have since been developed to improve local delivery and tolerability.
- Manufacturer: the specific manufacturer of Voltarol varies by market; in the UK it is typically supplied by licensed pharmaceutical firms that hold a marketing authorization from the Medicines and Healthcare products Regulatory Agency (MHRA).
Note: Diclofenac is also marketed under well‑known brand names such as Voltaren, Cataflam and Zymox. Our online pharmacy provides the generic equivalent of these branded products, offering the same active ingredient at a reduced cost.
How Voltarol Works
Diclofenac belongs to the arylacetic acid class of NSAIDs. Its therapeutic effect stems from the reversible inhibition of cyclo‑oxygenase (COX) enzymes—both COX‑1 and COX‑2. By blocking COX activity, diclofenac reduces the conversion of arachidonic acid to prostaglandins, which are lipid mediators responsible for pain signalling, fever and inflammation.
- Onset of action: oral diclofenac tablets typically begin to relieve pain within 30–60 minutes; topical gels may produce local analgesia within 15–30 minutes.
- Duration: the analgesic effect persists for 4–6 hours after a standard 50 mg dose, reflecting the drug’s plasma half‑life of approximately 1–2 hours.
- Clearance: diclofenac is metabolised primarily in the liver via oxidative pathways and excreted in the urine and bile; renal clearance accounts for about 30 % of eliminated drug.
Through this mechanism, diclofenac reduces peripheral sensitisation of nociceptors and curbs the inflammatory cascade that underlies many musculoskeletal disorders.
Conditions Treated with Voltarol
- Osteoarthritis – a common degenerative joint disease affecting roughly 8.5 % of adults in the UK. Diclofenac alleviates joint pain and stiffness by decreasing synovial inflammation.
- Rheumatoid arthritis – an autoimmune condition with a prevalence of .5–1 % in the UK adult population. The anti‑inflammatory action of diclofenac provides symptomatic relief while disease‑modifying agents are administered.
- Acute musculoskeletal injuries – sprains, strains, and tendonitis frequently present in sports and occupational settings. Prompt diclofenac therapy reduces swelling and facilitates functional recovery.
- Post‑operative pain – after orthopedic or dental procedures, diclofenac offers opioid‑sparing analgesia, contributing to faster mobilisation and reduced hospital stay.
- Bursitis and tendinopathy – localised inflammation of bursae and tendons responds well to topical diclofenac formulations, delivering high concentrations at the site of pathology with minimal systemic exposure.
These indications are authorised by the MHRA and are reflected in the British National Formulary (BNF) guidance for diclofenac use.
Who is Voltarol For?
- Adults with acute or chronic inflammatory pain who require rapid symptom control and have no contraindications to NSAIDs.
- Patients with osteoarthritis or rheumatoid arthritis who find paracetamol insufficient and prefer a non‑opioid analgesic.
- Individuals undergoing minor surgical or dental procedures where short‑term inflammation is expected.
- Athletes and active workers who experience soft‑tissue injuries and need topical relief without systemic side effects.
Contra‑indications include: a history of gastrointestinal ulceration or bleeding, severe renal impairment (eGFR < 30 mL/min/1.73 m²), uncontrolled hypertension, heart failure, known hypersensitivity to diclofenac or other NSAIDs, and pregnancy after the first trimester. In these situations, alternative analgesic strategies should be considered.
Risks, Side Effects, and Interactions
Common
- Nausea, dyspepsia, or mild abdominal discomfort.
- Headache or dizziness, particularly after the first dose.
- Skin irritation at the site of topical application (redness, itching).
Rare
- Elevated liver enzymes (ALT, AST) indicating hepatic stress.
- Mild elevation of blood pressure, especially in patients with pre‑existing hypertension.
- Phototoxic reactions with prolonged sun exposure when using topical gel.
Serious
- Gastrointestinal ulceration, bleeding or perforation, which may present as melena, haematemesis, or abdominal pain.
- Renal impairment manifested by reduced urine output, increased serum creatinine, or electrolyte disturbances.
- Cardiovascular events such as myocardial infarction or stroke, particularly in patients with established atherosclerotic disease.
- Severe hypersensitivity reactions, including Stevens‑Johnson syndrome or anaphylaxis.
Drug–drug interactions
- Anticoagulants (warfarin, direct oral anticoagulants) – additive risk of bleeding.
- Other NSAIDs or aspirin – increased gastrointestinal toxicity.
- ACE inhibitors, ARBs, diuretics – may amplify renal adverse effects.
- Lithium – diclofenac can raise serum lithium levels, risking toxicity.
- Methotrexate – reduced clearance of methotrexate may lead to myelosuppression.
Patients should disclose all concurrent medicines, including over‑the‑counter drugs and herbal supplements, to their healthcare provider before initiating diclofenac therapy.
Practical Use: Dosing, Missed Dose, Overdose
- Standard oral dosing: 50 mg diclofenac taken 1–3 times daily (maximum 150 mg per day). The dose may be adjusted based on pain severity and patient tolerance.
- Topical gel: Apply 2–4 g to the affected area three to four times daily; do not exceed 16 g per day.
- Patch formulation: One patch (containing 30 mg diclofenac) applied to clean, dry skin for up to 12 hours, then removed.
- Missed dose: If a dose is forgotten, take it as soon as remembered unless the next scheduled dose is close (within 4 hours). Do not double‑dose.
- Overdose: Signs may include nausea, vomiting, abdominal pain, gastrointestinal bleeding, or central nervous system depression. Seek immediate medical attention; treatment is symptomatic and may involve activated charcoal if presentation is early.
Precautions
- Take oral diclofenac with food or milk to minimise gastrointestinal irritation.
- Avoid excessive alcohol, which can heighten the risk of gastric bleeding.
- Patients with chronic kidney disease should be monitored for renal function; dose reduction or avoidance may be necessary.
- Use the lowest effective dose for the shortest duration consistent with clinical response.
Buying Voltarol from Our Online Pharmacy
Voltarol can be purchased directly from our online pharmacy in the UK. Our service offers several advantages designed for patient convenience and safety:
- Affordable pricing – we source generic diclofenac from reputable overseas manufacturers, delivering the product at near‑manufacturer cost, which translates into lower out‑of‑pocket expenses.
- Verified quality – each batch is supplied by licensed pharmacies that comply with Good Manufacturing Practice (GMP) standards and is inspected by independent quality agencies before dispatch.
- Guaranteed delivery – orders are packaged discreetly and shipped via a reliable courier network; standard delivery typically arrives within 7 days, while an express option delivers in 3–5 days.
- Online‑only access – patients who face limited local availability, insurance restrictions, or who prefer a private purchasing route can obtain the medication without visiting a physical pharmacy.
Our pharmacy operates as a broker service, collaborating with overseas licensed pharmacies and suppliers. This model enables a discreet service that respects patient privacy while maintaining compliance with UK import regulations for personal use. All shipments include clear labelling, patient information leaflets, and a tracking number to monitor progress.
FAQ
-
Is Voltarol available in both brand‑name and generic forms in the UK?
Yes. The active ingredient diclofenac is marketed under several brand names, including Voltaren and Cataflam, as well as generic versions produced by various pharmaceutical companies. Both formulations contain the same therapeutic compound and are authorised by the MHRA. -
What is the best way to store Voltarol tablets?
Store tablets at controlled room temperature (15–25 °C) in a dry place, protected from direct sunlight and moisture. Keep the container tightly closed and out of reach of children. -
Can I travel with Voltarol in my hand luggage?
Yes, diclofenac tablets and gel sachets are permitted in hand luggage for personal use. Ensure the product is in its original packaging, and carry a copy of the patient information leaflet to satisfy security personnel if requested. -
Does the gel formulation have a different expiry date than tablets?
Topical gels often have a slightly shorter shelf‑life due to the presence of excipients that can degrade with exposure to heat. Check the printed expiry date on the packaging; typically, gels remain stable for 24 months from the date of manufacture. -
Are there any specific warnings for elderly patients?
Older adults have an increased risk of gastrointestinal bleeding and renal impairment when using NSAIDs. Dose reduction, regular monitoring of renal function, and co‑administration of a gastro‑protective agent (e.g., a low‑dose proton pump inhibitor) may be advisable. -
Can diclofenac affect drug testing for athletes?
Diclofenac is not listed as a prohibited substance by the World Anti‑Doping Agency (WADA). However, athletes should disclose any medication use to their anti‑doping authority to avoid unintended consequences. -
What inactive ingredients are present in the tablet formulation?
Common excipients include lactose monohydrate, microcrystalline cellulose, magnesium stearate, and silicon dioxide. Patients with hypersensitivity to these substances should consult a pharmacist before use. -
Is personal import of Voltarol into the UK allowed?
The UK permits personal import of a three‑month supply of prescription‑only medicines for personal use, provided the product is sourced from a licensed overseas pharmacy and a valid prescription is held. Our online pharmacy ensures compliance with these regulations. -
Do regional formulations of diclofenac differ in bioavailability?
Minor variations in tablet coating or excipient composition can affect dissolution rates, but the overall bioavailability of diclofenac remains within the accepted therapeutic range across EU, US, and Asian formulations. -
How was diclofenac originally discovered?
Diclofenac was first synthesised in 1963 by Ciba‑Geigy (now part of Novartis) as part of a search for selective COX inhibitors. Clinical trials in the 197s demonstrated its efficacy in reducing inflammation, leading to its worldwide adoption as an NSAID.
Glossary
- Cyclo‑oxygenase (COX)
- An enzyme that converts arachidonic acid into prostaglandins, which mediate inflammation, pain and fever.
- Prostaglandin
- Lipid compounds that act locally to promote inflammation, increase blood flow, and sensitize nerves to pain.
- Gastro‑protective agent
- A medication such as a proton pump inhibitor or H2‑receptor antagonist used to reduce the risk of stomach ulceration caused by NSAIDs.
- Bioavailability
- The proportion of a drug that reaches systemic circulation unchanged after administration; a key determinant of therapeutic effect.
⚠️ Disclaimer
The information provided about Voltarol is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Voltarol for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.