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Generic Fliban Information
Introduction
Fliban (generic name Flibanserin) is a centrally acting medication developed to address hypo‑active sexual desire disorder (HSDD) in pre‑menopausal women. The drug belongs to the Women’s Health medication group and is marketed under the active compound Flibanserin. While the product has received regulatory approval in the United States (brand name Addyi), it is not licensed by the UK Medicines and Healthcare products Regulatory Agency (MHRA) for routine clinical use. Nevertheless, the compound is sometimes accessed through specialised overseas suppliers for women who have limited treatment options within the National Health Service (NHS).
What is Fliban?
Fliban is the generic version of Addyi, containing the same active compound Flibanserin. The medication was originally developed by Sprout Pharmaceuticals and later licensed to various generic manufacturers. Our online pharmacy provides this generic alternative as a cost‑effective treatment option for women seeking to improve low sexual desire.
How Fliban Works
Flibanserin acts on several neurotransmitter systems in the brain. It is a partial agonist at 5‑HT₁A receptors and an antagonist at 5‑HT₂A receptors; additionally, it modestly enhances dopamine and norepinephrine release while reducing serotonin activity. By shifting the balance toward excitatory neurotransmitters, the drug is thought to increase sexual interest and arousal. Clinical studies show a gradual therapeutic effect, typically emerging after 4 weeks of daily dosing and continuing for several months. The drug’s plasma half‑life is approximately 11 hours, and it is eliminated primarily via hepatic metabolism (CYP3A4).
Conditions Treated with Fliban
- Hypo‑active Sexual Desire Disorder (HSDD) in pre‑menopausal women – the primary indication. In the United Kingdom, prevalence estimates suggest that 10–15 % of adult women experience persistent low sexual desire that interferes with personal wellbeing.
- Off‑label use for sexual dysfunction related to antidepressant‑induced loss of libido – some clinicians consider Flibanserin when conventional sexual‑function agents are ineffective, although formal approval for this use is lacking in the UK.
The drug’s efficacy is linked to its central modulation of serotonergic and dopaminergic pathways, which are known to mediate sexual motivation.
Suitable Candidates for Fliban Treatment
- Women aged 18 – 64 years who are premenopausal, in a stable, consensual sexual relationship, and who have been diagnosed with HSDD after exclusion of medical, psychiatric, or hormonal causes.
- Patients who have tried first‑line interventions (e.g., counselling, lifestyle modification, hormonal therapy) without satisfactory improvement.
- Women without significant hepatic impairment, uncontrolled hypertension, or a history of severe alcohol‑related adverse reactions, as these conditions increase the risk of serious side effects.
Flibanserin is not appropriate for:
- Post‑menopausal women, men, or adolescents.
- Individuals taking potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin).
- Patients with a known hypersensitivity to Flibanserin or any excipients in the tablet formulation.
Risks, Side Effects, and Interactions
Common
- Dizziness or light‑headedness
- Nausea and mild gastrointestinal upset
- Sleepiness or somnolence (especially when taken at night)
- Dry mouth
Rare
- Fatigue or excessive sleep
- Headache of moderate intensity
- Mild increase in blood pressure (≤ 5 mmHg)
Serious
- Severe hypotension or syncope when combined with alcohol (≥ 2 standard drinks) – a contraindication documented by the FDA and reflected in UK safety literature.
- Serotonin syndrome when used concomitantly with other serotonergic agents (e.g., SSRIs, MAO inhibitors).
- Hepatic injury in patients with pre‑existing liver disease; liver function tests should be monitored periodically.
Drug–drug interactions
- Strong CYP3A4 inhibitors (ketoconazole, itraconazole, clarithromycin, ritonavir) increase Flibanserin exposure → risk of serious hypotension and sedation.
- Moderate CYP3A4 inhibitors (cimetidine, fluconazole) may require dose adjustment or avoidance.
- Co‑administration with alcohol is contraindicated; even low‑to‑moderate consumption can precipitate marked hypotension and syncope.
Patients should disclose all prescription, over‑the‑counter, and herbal products to their healthcare provider before initiating Fliban.
Practical Use: Dosing, Missed Dose, Overdose
- Standard dosing: 100 mg once daily, taken at bedtime. The tablet may be taken with or without food, but a consistent routine helps mitigate daytime somnolence.
- Missed dose: If a dose is forgotten, skip it and resume the regular nightly schedule. Do not take a double dose to “catch up.”
- Overdose: In case of accidental ingestion of more than the prescribed amount, seek urgent medical attention. Supportive care, monitoring of blood pressure, and observation for prolonged sedation are recommended.
- Precautions:
- Avoid alcohol entirely while using Flibanserin.
- Do not start or stop the medication without professional guidance, especially if you have cardiovascular disease, hepatic impairment, or are pregnant/breast‑feeding.
- Store tablets at room temperature (15‑30 °C), protected from moisture and direct sunlight.
Buying Fliban from Our Online Pharmacy
Fliban can be purchased from our online pharmacy in UK with a streamlined, discreet ordering process. Our service offers:
- Affordable pricing that approaches the manufacturer’s cost, making generic Flibanserin accessible to patients who face high out‑of‑pocket expenses.
- Verified quality sourced from licensed overseas wholesalers that comply with Good Manufacturing Practice (GMP) standards.
- Guaranteed delivery – express shipping within 7 days for most EU orders, and regular airmail that typically arrives in 3 weeks for non‑EU destinations.
- Online‑only access to international medications, enabling patients in regions where Fliban is not locally available to obtain the treatment legally.
We operate as a pharmacy broker service, partnering with overseas licensed pharmacies and reputable suppliers. This model allows us to maintain a discreet service that respects patient privacy while ensuring that each product meets stringent safety and authenticity criteria.
FAQ
-
What is the typical appearance of a Fliban tablet?
Fliban tablets are white, round, film‑coated pills pressed to 100 mg of Flibanserin. They usually bear “FLIBAN” imprinted on one side and a batch code on the other. -
Can Fliban be stored in a bathroom cabinet?
No. The medication should be kept in a dry, temperature‑controlled environment. Storing it in a bathroom, where humidity fluctuates, may degrade the active ingredient and reduce efficacy. -
Is Fliban affected by travel across time zones?
Flibanserin has a half‑life of about 11 hours, so traveling across time zones does not require dosage adjustment. However, maintaining the same bedtime administration helps minimise daytime sleepiness. -
Does Fliban have different formulations in the US versus the EU?
The core active ingredient (Flibanserin 100 mg) remains the same, but excipients such as fillers or coating agents may vary due to regional regulatory requirements. These differences are not expected to alter therapeutic effect. -
Are there specific warnings for women of Asian descent?
No ethnicity‑specific warnings have been issued by the FDA or MHRA. However, cultural variations in alcohol use patterns may influence the risk of alcohol‑related hypotension, so all patients should avoid alcohol while taking Flibanserin. -
Can Fliban be imported for personal use without a prescription in the UK?
Under the UK’s “personal import” exemption, individuals may import a three‑month supply of an unlicensed medication for personal use, provided they have a valid prescription from a UK‑registered prescriber. Importing without a prescription is not permitted. -
What are the consequences of mixing Fliban with over‑the‑counter sleep aids?
Combining Flibanserin with sedating OTC products (e.g., diphenhydramine) may amplify central nervous system depression, leading to excessive drowsiness or impaired coordination. Consultation with a healthcare professional is advised before co‑use. -
How does Flibanserin differ from traditional testosterone therapy for low libido?
Testosterone primarily acts peripherally and is approved for men; its efficacy in women is limited and associated with androgenic side effects. Flibanserin targets central neurotransmission, offering a gender‑specific mechanism without androgenic risks. -
Is there a risk of Fliban showing up on drug‑testing panels?
Flibanserin is not a controlled substance and is not included in standard workplace drug‑testing panels. Routine screening should not detect its presence. -
What is the shelf‑life of Fliban tablets after they are received?
Most manufacturers assign a 24‑month expiry from the date of manufacture. Patients should verify the “use by” date printed on the packaging and discard any tablets beyond this period.
Glossary
- 5‑HT₁A receptor
- A subtype of serotonin receptor that, when activated, typically produces anxiolytic and mood‑enhancing effects. Flibanserin’s partial agonism at this receptor is considered central to its therapeutic action.
- CYP3A4
- An enzyme of the cytochrome P450 family responsible for metabolising many drugs, including Flibanserin. Inhibitors of CYP3A4 can raise plasma levels of Flibanserin, increasing the risk of adverse effects.
- Hypo‑active Sexual Desire Disorder (HSDD)
- A persistent lack of sexual desire that causes personal distress or interpersonal difficulty, diagnosed after ruling out medical, psychiatric, or relational causes.
- Serotonin syndrome
- A potentially life‑threatening condition caused by excessive serotonergic activity, characterised by agitation, hyperthermia, autonomic instability, and neuromuscular abnormalities.
⚠️ Disclaimer
The information provided about Fliban is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Fliban for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.