Generic Ponstel

Ponstel is an anti-inflammatory drug used to treat primary dysmenorrhea and relieve of mild to moderate pain caused by periods in women.

Buy online · Medical info

  • Category: Women's Health
  • Active ingredient: Mefenamic Acid
  • Available Dosage: 250mg, 500mg
  • Payment options: VISA, Mastercard, Amex, JCB, Dinners
  • Delivery time: Airmail (10 - 21 days), EMS Trackable (5-9 days)

Buy Generic Ponstel Online

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500mg x 360 pills
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Medical Conditions

Generic Ponstel is used to treat or prevent the following medical conditions or diceases:

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Generic Ponstel information

Introduction

Ponstel is a non‑steroidal anti‑inflammatory drug (NSAID) marketed for the relief of moderate pain associated with menstrual cramps and other acute painful conditions. Its active ingredient is mefenamic acid, a propionic‑acid class NSAID that inhibits prostaglandin synthesis. In the United Kingdom, Ponstel is classified under the Women’s Health therapeutic group, although it is also prescribed for short‑term management of postoperative and musculoskeletal pain when NSAID therapy is appropriate. The medication is manufactured by several pharmaceutical companies under licence; the formulation sold as Ponstel contains 250 mg of mefenamic acid per tablet.


What is Ponstel?

Ponstel is a branded preparation of the generic compound mefenamic acid. It belongs to the propionic‑acid subclass of NSAIDs, sharing pharmacological properties with drugs such as ibuprofen and naproxen. The product is supplied in film‑coated tablets, each delivering a fixed dose of 250 mg mefenamic acid. The medication was developed in the 196s as a targeted treatment for dysmenorrhoea and has since been approved for a range of short‑term painful conditions. The manufacturer(s) authorised to market Ponstel in the UK must comply with the Medicines and Healthcare products Regulatory Agency (MHRA) standards for quality, safety and efficacy.


How Ponstel Works

Mefenamic acid exerts its therapeutic effect by reversibly inhibiting both cyclo‑oxygenase‑1 (COX‑1) and cyclo‑oxygenase‑2 (COX‑2) enzymes. These enzymes catalyse the conversion of arachidonic acid to prostaglandins, which are key mediators of inflammation, pain sensitisation, and fever. By reducing prostaglandin synthesis, Ponstel diminishes the peripheral sensitisation of nociceptors and the central perception of pain.

Onset of analgesia typically occurs within 30‑60 minutes after oral ingestion, with peak plasma concentrations reached at approximately 2 hours. The drug elimination half‑life averages 2‑4 hours, and renal excretion accounts for the majority of clearance. Because the inhibition of COX enzymes is reversible, normal prostaglandin production resumes as the drug is eliminated, limiting the duration of anti‑inflammatory activity to a few hours after each dose.


Conditions Treated with Ponstel

  • Primary dysmenorrhoea – painful menstrual cramps affecting up to 30 % of women of reproductive age in the UK. Mefenamic acid is recommended as a first‑line NSAID for women who do not achieve adequate relief with paracetamol.
  • Acute postoperative pain – short‑term use after minor surgical procedures (e.g., dental extraction, dermatological surgery) when opioid avoidance is desirable.
  • Musculoskeletal pain – sprains, strains minor soft‑tissue injuries where rapid analgesia is needed.
  • Renal colic (adjunct) – occasionally used as part of multimodal analgesia for ureteric stone pain, under specialist supervision.

Clinical guidelines (e.g., NICE NG114) endorse NSAIDs, including mefenamic acid, for these indications when contraindications such as active gastrointestinal ulceration or severe renal impairment are absent.


Who is Ponstel For?

Ponstel is appropriate for adult patients (≥ 18 years) who require short‑term relief from moderate pain that is inflammatory in nature. Typical candidates include:

  • Women experiencing painful menstrual cycles who have not responded to paracetamol or lifestyle measures.
  • Individuals who have undergone minor surgical procedures and need analgesia for up to 72 hours.
  • Patients with acute soft‑tissue injuries who prefer oral NSAID therapy over topical agents.

indications preclude use in:

  • Patients a known hypersensitivity to mefenamic acid, other NSAIDs, or any excipients in the tablet.
  • Individuals with active peptic ulcer disease, recent gastrointestinal bleeding, or severe hepatic impairment.
  • Pregnant women beyond 20 weeks gestation; NSAIDs associated with fetal cardiovascular risks after this stage.
  • Children and adolescents under 18 years, as data for mefenamic acid in this population are limited.

Healthcare professionals should evaluate cardiovascular risk, renal function, and concomitant medication before initiating Ponstel.


Risks, Side Effects, and Interactions

Common

  • Dyspepsia, abdominal discomfort
  • Nausea, occasional vomiting
  • Headache
  • Dizziness or light‑headedness

These effects are usually mild and transient. Taking Ponstel with food or a full glass of water can minimise gastrointestinal irritation.

Rare

  • Gastric or duodenal ulceration without prior ulcer history
  • Elevated liver enzymes (transaminases)
  • Peripheral oedema

Patients experiencing persistent abdominal pain, melena, or unexplained weight loss should seek medical advice promptly.

Serious

  • Gastro‑intestinal bleeding or perforation, presenting with haematemesis, melena, or severe abdominal pain
  • Severe hypersensitivity reactions, including Stevens‑Johnson syndrome, toxic epidermal necrolysis, or anaphylaxis
  • Acute renal failure, particularly in dehydrated individuals or those with pre‑existing renal disease

If any serious adverse event is suspected, the medication should be discontinued immediately and emergency care obtained.

Clinically Relevant Drug Interactions
  • Anticoagulants (e.g., warfarin, direct oral anticoagulants): increased bleeding risk; monitor coagulation parameters.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal and renal toxicity; concurrent use is generally discouraged.
  • Selective serotonin reuptake inhibitors (SSRIs and selective norepinephrine reuptake inhibitors (SNRIs): heightened risk of gastrointestinal bleeding.
  • Angiotensin‑converting enzyme (ACE) inhibitors, angiotensin‑II receptor blockers (ARBs), or diuretics: may reduce renal perfusion; monitor renal function.
  • Lithium: NSAIDs can raise serum lithium levels; check lithium concentrations if co‑administered.

Patients should disclose all current medications, including over‑the‑counter products and herbal supplements, to their prescriber.


Practical Use: Dosing, Missed Dose, Overdose

  • Standard adult dose: 250 mg taken orally with a glass of water. For dysmenorrhoea, the recommended regimen is one tablet every 6 hours, not to exceed three tablets in a 24‑hour period.
  • Maximum duration: Use should not exceed 4 days without medical review, as the risk of adverse events rises with prolonged exposure.
  • Missed dose: If a scheduled dose is forgotten, take it as soon as remembered unless it is within 2 hours of the next scheduled dose. Do not double‑dose to compensate.
  • Overdose: Symptoms may include severe nausea, vomiting, abdominal pain, dizziness, and blurred vision. In case of suspected overdose, seek urgent medical assistance; activated charcoal may be considered if presentation is early.
  • Food and alcohol: Taking Ponstel with meals reduces gastric irritation. Alcohol should be limited, as concurrent intake accentuates gastrointestinal bleeding risk.
  • Comorbidities: Patients with asthma, chronic kidney disease, or established cardiovascular disease require careful assessment before initiating therapy.

Buying Ponstel from Our Online Pharmacy

Ponstel can be purchased safely from our online pharmacy in the UK. We source the medication from vetted, MHRA‑approved suppliers, ensuring that every tablet meets the same quality standards as those dispensed in brick‑and‑mortar pharmacies.

  • Affordable pricing: Our cost structure mirrors manufacturer‑level pricing, passing savings directly to you.
  • Verified quality: All batches undergo third‑party testing for potency, purity, and sterility before shipment.
  • Guaranteed delivery: Choose discreet express shipping (delivery within 7 days) or standard airmail (approximately 3 weeks). Packaging is plain and secure to protect privacy.
  • International access: As a pharmacy broker service, we collaborate with licensed overseas pharmacies, expanding the range of medications available to UK residents who may face limited local stock or high retail prices.

Our service offers a reliable, low‑cost alternative for patients who need timely access to Ponstel while maintaining strict confidentiality.


FAQ

  • Can Ponstel be used for chronic pain conditions?
    Ponstel is intended for short‑term use, typically no longer than four days. Chronic pain requires long‑acting agents or alternative treatment strategies; prolonged NSAID therapy increases the risk of gastrointestinal, renal and cardiovascular complications.

  • Is there a difference between Ponstel tablets and generic mefenamic acid capsules?
    Both contain the same active ingredient, mefenamic acid, and provide equivalent analgesic efficacy when dosed appropriately. Differences may exist in excipients, tablet coating, or capsule size, which could affect tolerability for individuals with specific sensitivities.

  • What should I do if I experience a skin rash while taking Ponstel?
    A mild rash may resolve after discontinuation, but any sign of a spreading rash, blistering, or mucosal involvement warrants immediate medical evaluation, as it could indicate a serious hypersensitivity reaction such as Stevens‑Johnson syndrome.

  • Does Ponstel interact with hormonal contraceptives?
    No clinically significant pharmacokinetic interaction has been documented between mefenamic acid and combined oral contraceptives. However, NSAIDs can occasionally increase menstrual bleeding, which may affect perceived contraceptive efficacy; discuss any concerns with a healthcare professional.

  • Can I travel internationally with a supply of Ponstel?
    Yes, provided the medication is in its original packaging, labelled with the generic name and strength, and accompanied by a copy of the prescription or a qualified health‑care professional’s note if required by the destination country’s customs regulations.

  • How should Ponstel be stored in hot climates?
    Store tablets at controlled room temperature (15 °C–30 °C) away from direct sunlight and humidity. In particularly hot environments, keep the medication in a sealed container within a cool, dry place, such as a cabinet away from radiators.

  • Are there any known differences in formulation between UK‑marketed Ponstel and versions sold elsewhere?
    The active ingredient and dosage strength are consistent worldwide, but filler substances (e.g., lactose, magnesium stearate) may vary. Patients with specific excipient allergies should review the full ingredient list provided by the supplier.

  • Is Ponstel safe for patients with a history of asthma?
    Although mefenamic acid is not a common trigger for aspirin‑exacerbated respiratory disease, NSAIDs can precipitate bronchospasm in a subset of asthmatic patients. Those with known NSAID‑sensitive asthma should avoid Ponstel and seek alternative analgesics.

  • Can Ponstel affect routine blood tests?
    NSAIDs may cause a mild, transient increase in serum creatinine and a reduction in platelet aggregation. Routine liver function tests can also show slight elevations in transaminases. Clinicians often monitor these parameters if treatment extends beyond a few days.

  • What is the environmental impact of disposing unused Ponstel tablets?
    Unused NSAID tablets should not be flushed down the toilet or thrown in household waste. Return them to a pharmacy’s medicine take‑back program or waste guidelines to minimise environmental contamination.


Glossary

Cyclo‑oxygenase (COX)
An enzyme family (COX‑1 and COX‑2) that converts arachidonic acid into prostaglandins, which mediate inflammation, pain, and fever.
Prostaglandin
Lipid compounds that act locally to enhance inflammation, sensitize nerve endings to pain, and regulate gastric mucus production.
Reversible inhibition
Temporary binding of a drug to an enzyme that can be displaced, allowing normal enzyme activity to resume once the drug is cleared.
Stevens‑Johnson syndrome
A rare, severe cutaneous adverse reaction characterised by widespread skin detachment and mucous membrane involvement, requiring urgent medical care.

⚠️ Disclaimer

The information provided about Ponstel is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Ponstel for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.

Alternative names or trademarks of Generic Ponstel

Ponstel may be marketed under different names in various countries. All of them contain Mefenamic Acid as main ingredient. Some of them are the following:

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Information about ordering Generic Ponstel online

Buy placing an order on our website you must agree to the following: Your are above 18 years old, You do not have any contraindications to mefenamic acid so you can use Generic Ponstel safely, We do not provide any paper instructions, side effect warnings or usage directions with medication Ponstel. They are available only online on our website. We do not provide any doctors consultation -- please consult with your doctor before using this medication. We provide you a cheap alternative to save cost but we cannot replace real practioning medical specialist. When you order Generic Ponstel without a prescription you agreee that you will get generic pills manufactured in Inida, they will be shipped to you in anonymous package except you ordered traceable delivery. From our side we guarantee quality of Generic Ponstel - mefenamic acid medication that is sold through our site. We do our best and send medication in a valid condition and safely packed, however we may not guarantee worry free delivery to some countries where strict customs rules may apply. If you have questions do not hesitate to call us or use Live chat. After you place your order we may call you back for verification purposes.

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