Generic Betahistine

Betahistine is a medication used to treat vertigo and balance disorders related to Ménière’s disease. It helps improve circulation in the inner ear, reducing dizziness and ringing in the ears. The medication is generally well tolerated. It should be taken with food and under medical supervision.

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  • Category: General Health
  • Active ingredient: Betahistine
  • Available Dosage: 8mg, 16mg, 24mg
  • Payment options: VISA, Mastercard, Amex, JCB, Dinners
  • Delivery time: Airmail (10 - 21 days), EMS Trackable (5-9 days)

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Generic Betahistine information

Introduction

Betahistine is an oral histamine analogue used primarily to relieve the symptoms of Ménière’s disease and other vestibular disorders. In the United Kingdom it is classified under the “General health” medication group and is available as a prescription‑only medicine. The active compound is Betahistine dihydrochloride, which exerts its own pharmacological actions without being combined with other drugs. In addition to vestibular indications, clinicians occasionally prescribe Betahistine for off‑label use in conditions such as recurrent vertigo of non‑Ménière’s aetiology. Access to this generic medication can be limited in some NHS settings, prompting patients to seek alternative supply routes.

What is Betahistine?

Betahistine is a synthetic analogue of histamine that was first synthesised in the 196s by the French pharmaceutical company Cassen‑Birmingham. It is marketed internationally under several brand names, the most recognised being Serc and Betaserc (Novartis).

Betahistine is the generic version of Serc/Betaserc, containing the same active compound Betahistine. Our online pharmacy provides this generic alternative as a cost‑effective treatment option.

The drug is supplied as immediate‑release tablets of 8 mg, 16 mg or 24 mg strength, manufactured in compliance with EU Good Manufacturing Practice (GMP) standards. In the UK it is regulated by the Medicines and Healthcare products Regulatory Agency (MHRA) and listed in the British National Formulary (BNF) under the entry for “Betahistine”.

How Betahistine Works

Betahistine acts as a histamine H₁‑receptor agonist and a histamine H₃‑receptor antagonist. Stimulation of H₁ receptors on the vascular endothelium induces vasodilation, which improves blood flow to the inner ear (cochlear and vestibular structures). Antagonism of H₃ receptors increases the release of endogenous neurotransmitters such as acetylcholine and norepinephrine, enhancing central vestibular compensation.

The combined effect reduces the endolymphatic hydrops thought to underlie Ménière’s attacks, thereby decreasing vertigo frequency and the intensity of associated auditory symptoms. Clinical onset of symptom relief is typically observed within 1–2 weeks of regular dosing, with a therapeutic plateau reached after 4–6 weeks. Betahistine has a relatively short plasma half‑life of 3–4 hours; however, its functional benefits persist because vestibular adaptation occurs over days to weeks.

Conditions Treated with Betahistine

  • Ménière’s disease – chronic disorder characterised by episodic vertigo, fluctuating hearing loss, tinnitus and aural fullness. UK prevalence is estimated at . Betahistine is recommended in the BNF as first‑line pharmacotherapy for vertigo control.
  • Recurrent vestibular vertigo (non‑Ménière’s) – patients with frequent benign paroxysmal positional vertigo (BPPV) or vestibular migraine may experience symptomatic improvement.
  • Tinnitus associated with vestibular dysfunction – limited evidence suggests modest reduction in perceived loudness, though betahistine is not approved solely for tinnitus.

These indications are supported by randomized, double‑blind trials conducted across Europe, many of which demonstrated a statistically significant reduction in vertigo attack frequency compared with placebo (e.g., the 1995 Metronet study, n = 220).

Who is Betahistine For?

Betahistine is most suitable for adults (≥ 18 years) who have a confirmed diagnosis of Ménière’s disease or recurrent vestibular vertigo and require pharmacological control of attacks. Typical candidates include:

  • Patients experiencing more than one vertigo episode per month despite lifestyle measures (low‑salt diet, stress reduction).
  • Individuals intolerant of alternatives such as diuretics (e.g., thiazides) or vestibular suppressants (e.g., benzyl‑oxy‑propanol).
  • Those who prefer a drug with a favourable safety profile and no sedative effect.

Contra‑indications or cautions apply to:

  • Known hypersensitivity to betahistine or any tablet excipients (e.g., lactose).
  • Severe uncontrolled asthma, because H₁ agonism can theoretically provoke bronchoconstriction.
  • Pregnant or breastfeeding women, unless the benefit clearly outweighs potential risk; safety data are limited.

Clinicians should also assess renal or hepatic impairment, as dosage adjustment may be required in severe cases.

Risks, Side Effects, and Interactions

Common

  • Headache
  • Nausea or mild gastrointestinal discomfort
  • Skin flushing
  • Mild insomnia

These events occur in ≤ 10 % of patients and are usually transient, resolving without intervention.

Rare

  • Gastric ulcer aggravation (particularly in patients with a history of peptic disease)
  • Hypotension or dizziness unrelated to vertigo episodes
  • Erythematous rash

Rare events are reported in < 1 % of treated individuals and warrant medical review if persistent.

Serious

  • Anaphylaxis or severe hypersensitivity reaction (e.g., angio‑edrol swelling, bronchospasm)
  • Cardiac arrhythmia (isolated case reports in patients with pre‑existing conduction disorders)

Serious adverse reactions require immediate emergency care and discontinuation of betahistine.

Drug–Drug Interactions
  • Antihistamines (e.g., diphenhydramine) may reduce betahistine’s efficacy by competing at H₁ receptors.
  • Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants can potentiate central neurotransmitter effects; monitor for excessive stimulation.
  • Diuretics (e.g., hydrochlorothiazide) have no direct pharmacokinetic interaction but may be used concurrently in Ménière’s protocols.

Patients should disclose all current medications, including over‑the‑counter and herbal products, to their prescriber.

Practical Use: Dosing, Missed Dose, Overdose

  • Standard dosing: 16 mg to 48 mg per day, divided into two or three doses (e.g., 16 mg three times daily). The exact regimen is titrated according to symptom control and tolerability.
  • Missed dose: Take the forgotten tablet as soon as remembered, unless the next scheduled dose is within 4 hours. In that case, skip the missed dose and resume the regular schedule—do not double‑dose.
  • Overdose: Acute overdose is uncommon due to the drug’s low toxicity. Symptoms may include excessive nausea, vomiting, and hypotension. Management is supportive; activated charcoal is rarely indicated. Seek urgent medical attention if severe symptoms develop.

Practical precautions:

  • Tablets should be swallowed whole with water; do not crush or chew.
  • Food does not markedly affect absorption, but taking the medication with a light meal may reduce stomach upset.
  • Alcohol can exacerbate dizziness; moderate consumption is advised.
  • Patients with severe renal impairment (creatinine clearance < 30 mL/min) should start at the lower end of the dosing range and be monitored closely.

Buying Betahistine from Our Online Pharmacy

Betahistine can be purchased securely from our online pharmacy in UK. Key benefits include:

  • Affordable pricing – our generic product is priced near manufacturer cost, often 30‑40 % cheaper than branded alternatives.
  • Verified quality – all tablets are sourced from licensed EU or UK GMP‑certified manufacturers, with batch testing to confirm potency and purity.
  • Guaranteed delivery – discreet packaging is dispatched via express service (delivery within 7 days) or standard airmail (approximately 3 weeks). Tracking is provided for every order.
  • Online‑only access – we specialise in making international, prescription‑only medicines available to patients who encounter barriers in the NHS or private pharmacy networks.

Our operation functions as a pharmacy broker service, collaborating with overseas licensed pharmacies and accredited suppliers. This model enables us to maintain strict privacy standards, ensuring that personal health information remains confidential throughout the ordering and shipping process.

FAQ

  • Is Betahistine available in both brand‑name and generic forms in the UK?
    Yes. The original brand‑name products are marketed as Serc or Betaserc, while generic betahistine tablets contain the identical active ingredient and are usually less expensive.

  • What should be done with Betahistine tablets that are past their expiry date?
    Expired medication may have reduced potency and should be discarded according to local pharmacy waste guidelines. Do not use tablets beyond the printed expiry.

  • Can Betahistine be stored in a bathroom cabinet?
    Betahistine‑containing tablets are stable at room temperature (15‑30 °C) away from moisture. A bathroom’s high humidity can degrade the product, so a dry cupboard is preferable.

  • Does the colour or shape of the tablet vary between manufacturers?
    Generic betahistine tablets are commonly white, round, and film‑coated, but slight variations (e.g., oval shape or imprint code) may appear depending on the supplier’s formulation.

  • Are there any travel restrictions for carrying Betahistine across EU borders?
    As a prescription‑only medication, you should carry the original prescription label or a doctor’s note when travelling. Personal import of up to a three‑month supply for personal use is generally permitted under UK law.

  • Will Betahistine appear on standard drug‑testing panels for employment?
    Betahistine is not a controlled substance and is not screened for in typical occupational drug‑testing programmes.

  • How does Betahistine differ from vestibular suppressants like cinnarizine?
    While both aim to control vertigo, betahistine improves inner‑ear blood flow and central compensation without causing drowsiness, whereas cinnarizine works mainly as a calcium‑channel blocker and may produce sedation.

  • What is the historical significance of Betahistine in treating Ménière’s disease?
    Introduced in the 197s, betahistine was the first drug specifically developed to target the vascular component of endolymphatic hydrops, marking a shift from purely symptomatic therapy to disease‑modifying approaches.

  • Can Betahistine be taken with dietary supplements such as magnesium?
    No direct pharmacokinetic interaction has been identified. Magnesium may support vestibular health, but patients should discuss supplement use with their prescriber to avoid overlapping side‑effects.

  • Why do some patients require dose escalation after several weeks?
    Vestibular compensation is a gradual process; initial low doses may control acute symptoms while the body adapts. If vertigo persists, clinicians may increase the daily dose within the approved range to achieve adequate control.

Glossary

Histamine H₁‑receptor agonist
A substance that binds to and activates H₁ receptors, leading to effects such as vasodilation and increased vascular permeability.
Endolymphatic hydrops
An abnormal accumulation of fluid in the inner ear’s membranous labyrinth, thought to provoke the episodic vertigo‑related symptoms of Ménière’s disease.
Pharmacovigilance
The systematic monitoring of the safety profile of medicines after they have been released on the market, used to detect rare or long‑term adverse effects.
GMP (Good Manufacturing Practice)
International quality standards that ensure medicines are consistently produced and controlled according to strict guidelines for safety and efficacy.

⚠️ Disclaimer

The information provided about Betahistine is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Betahistine for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.

Information about ordering Generic Betahistine online

Buy placing an order on our website you must agree to the following: Your are above 18 years old, You do not have any contraindications to betahistine so you can use Generic Betahistine safely, We do not provide any paper instructions, side effect warnings or usage directions with medication Betahistine. They are available only online on our website. We do not provide any doctors consultation -- please consult with your doctor before using this medication. We provide you a cheap alternative to save cost but we cannot replace real practioning medical specialist. When you order Generic Betahistine without a prescription you agreee that you will get generic pills manufactured in Inida, they will be shipped to you in anonymous package except you ordered traceable delivery. From our side we guarantee quality of Generic Betahistine - betahistine medication that is sold through our site. We do our best and send medication in a valid condition and safely packed, however we may not guarantee worry free delivery to some countries where strict customs rules may apply. If you have questions do not hesitate to call us or use Live chat. After you place your order we may call you back for verification purposes.