Filitra

Introduction

Filitra is a medication that contains the phosphodiesterase‑type‑5 (PDE5) inhibitor vardenafil. It is classified for the treatment of erectile dysfunction (ED) and other aspects of men’s health. The product is marketed in the United Kingdom for adult men who experience difficulty achieving or maintaining an erection sufficient for sexual activity. Vardenafil is also the active ingredient in well‑known brand‑name preparations such as Levitra and Staxyn, and Filitra provides a cost‑effective generic alternative.

What is Filitra?

• Filitra is a tablet formulation that delivers a fixed dose of vardenafil, a selective PDE5 inhibitor.
• The medication is produced by manufacturers that adhere to United Kingdom Good Manufacturing Practice (GMP) standards; the specific company may vary between suppliers.
• Generic statement: Filitra is the generic version of Levitra, containing the same active compound vardenafil. Our online pharmacy provides this generic alternative as a cost‑effective treatment option.

The tablet is developed for oral administration, typically available in 5 mg, 10 mg, and 20 mg strengths. Inactive ingredients may include lactose, microcrystalline cellulose, magnesium stearate, and other excipients that aid tablet integrity and dissolution.

How Filitra Works

Vardenafil, like other PDE5 inhibitors, blocks the enzyme phosphodiesterase type 5. This enzyme degrades cyclic guanosine monophosphate (cGMP), a messenger that relaxes smooth muscle in the corpus cavernosum. By inhibiting PDE5, vardenafil increases cGMP levels when sexual stimulation releases nitric oxide (NO) in the penile tissue. The elevated cGMP causes smooth‑muscle relaxation, allowing blood to fill the corpora cavernosa, producing an erection.

Key pharmacokinetic points:

• Onset of action: Most men report an erection within 30–60 minutes after ingestion.
• Peak plasma concentration: Reached 1–2 hours after oral dose.
• Duration of effect: Therapeutic benefit can last up to 4–5 hours, depending on dose and individual metabolism.
• Elimination: Vardenafil is primarily metabolised by hepatic CYP3A4 enzymes; the average half‑life is approximately 4–5 hours.

Because the drug requires sexual arousal to initiate NO release, Filitra does not cause a spontaneous erection.

Conditions Treated with Filitra

• Erectile Dysfunction (ED): The primary indication. In the UK, an estimated 8 million men experience ED at some point in their lives, representing a substantial burden on sexual health services.
• Pulmonary arterial hypertension (off‑label): While vardenafil is not licensed for this purpose in the UK, some clinicians explore its vasodilatory properties in experimental settings.
• Secondary benefit in men with diabetes‑related vascular dysfunction: Vardenafil improves endothelial function, which may support erectile performance in diabetic patients, though it remains an adjunct to standard diabetes management.

Filitra’s efficacy for ED is supported by multiple randomized, double‑blind, placebo‑controlled trials published in peer‑reviewed journals, demonstrating statistically significant improvements in International Index of Erectile Function (IIEF) scores versus placebo.

Suitable Candidates for Filitra Treatment

• Adult men (≥18 years) with diagnosed erectile dysfunction: Those who have failed lifestyle modifications or require pharmacological assistance.
• Patients with mild to moderate cardiovascular disease: Men whose cardiologists have cleared them for sexual activity and confirm that they are not using nitrates.
• Individuals with stable diabetes mellitus: Provided glycaemic control is adequate and no contraindicating comorbidities exist.

Situations where Filitra may be inappropriate:

• Concurrent nitrate therapy: Co‑administration can cause severe hypotension.
• Severe liver impairment (Child‑Pugh class C): May result in excessive drug exposure.
• Known hypersensitivity to vardenafil or any tablet excipient.
• Retinitis pigmentosa or other retinal disorders: PDE5 inhibitors have been associated with rare visual disturbances.

Risks, Side Effects, and Interactions

Common

• Headache
• Flushing (warmth, redness of face or neck)
• Nasal congestion or runny nose
• Dyspepsia (indigestion)
• Back pain or muscle aches (often mild and transient)

These effects typically resolve within a few hours and are dose‑related.

Rare

• Visual disturbances (blurred vision, colour perception changes)
• Hearing loss or tinnitus
• Prolonged erection (priapism) lasting >4 hours, which requires urgent medical attention

Serious

• Priapism: Persistent erection can cause permanent erectile tissue damage. Immediate medical evaluation is essential.
• Severe hypotension: Particularly when combined with nitrates, alpha‑blockers, or potent antihypertensives.
• Allergic reactions: Manifesting as rash, swelling, or anaphylaxis.

Drug–Drug Interactions

• Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Contraindicated; may cause dangerous drops in blood pressure.
• Alpha‑blockers (e.g., doxazosin, tamsulosin): Use with caution; monitor blood pressure.
• CYP3A4 inhibitors (e.g., ketoconazole, erythromycin, HIV protease inhibitors): May increase vardenafil plasma concentrations, necessitating dose reduction.
• CYP3A4 inducers (e.g., rifampicin, phenytoin): May lower drug levels, potentially reducing efficacy.

Patients should disclose all prescribed, over‑the‑counter, and herbal products to their healthcare professional before initiating Filatra.

Practical Use: Dosing, Missed Dose, Overdose

• Starting dose: For most men, a 10 mg tablet taken orally, with or without food, approximately 30 minutes before anticipated sexual activity.
• Dose titration: Based on effectiveness and tolerability, the dose may be increased to 20 mg or decreased to 5 mg. The maximum recommended dose is 20 mg per day.
• Maximum frequency: No more than one tablet within a 24‑hour period.

Missed dose: If a dose is forgotten and the planned sexual activity is still at least 30 minutes away, the tablet may be taken. If the scheduled activity is less than 30 minutes away, the missed dose should be omitted; do not double‑dose.

Overdose: In the event of an accidental ingestion of more than the prescribed amount, seek immediate medical attention. Symptoms of overdose may include profound hypotension, severe headache, or persistent erection.

Food and alcohol considerations: A high‑fat meal can delay onset by up to 1 hour. Moderate alcohol consumption does not significantly affect efficacy, but excessive drinking may potentiate hypotensive effects.

Comorbidities: Men with renal impairment (eGFR < 30 mL/min) should start at the lowest dose (5 mg) and may require further adjustment.

Buying Filitra from Our Online Pharmacy

Filitra can be purchased directly from our online pharmacy in the UK. Our service offers several advantages for patients seeking a reliable, discreet, and affordable solution:

• Affordable pricing: Prices are set close to manufacturer cost, providing a lower‑than‑retail option for the generic product.
• Verified quality: All tablets are sourced from licensed overseas pharmacies that comply with Good Manufacturing Practice and are inspected by independent quality‑assurance bodies.
• Guaranteed delivery: Discreet packaging is shipped to the UK address of the customer. Standard delivery typically arrives within 7 days (express) or approximately 3 weeks via regular airmail for remote locations.
• Online‑only access: The pharmacy broker model enables us to dispense international medications that may not be stocked in local high‑street pharmacies, ensuring continuity of treatment for men with limited access.

Our platform respects patient privacy, using secure payment gateways and confidential handling of all orders. The service is designed for adults who are capable of making informed health decisions and who may lack convenient access to traditional pharmacy services or insurance‑based prescriptions.

FAQ

• Is Filitra available in both brand‑name and generic forms in the UK?
  Filitra is marketed as a generic product. The original brand‑name formulation containing vardenafil is known as Levitra. Both versions contain the same active ingredient, but Filitra is typically offered at a lower price point.

• What is the best way to store Filitra tablets?
  Store the tablets at room temperature (15 °C–30 °C). Keep them away from direct sunlight, moisture, and strong heat sources. Do not refrigerate or freeze the medication.

• Can Filitra be safely imported into the UK for personal use?
  Personal import of a prescription‑only medication like Filitra is permitted under UK law when the buyer holds a valid prescription. Our online pharmacy ensures that all imported tablets comply with MHRA regulations and are shipped with appropriate customs documentation.

• Does the appearance of Filitra tablets differ from brand‑name vardenafil?
  Filitra tablets are typically round, film‑coated, and bear a distinct imprint indicating the strength (e.g., “F10” for 10 mg). Brand‑name Levitra tablets may have a different colour and imprint. Both formulations dissolve similarly.

• Are there any regional formulation differences for vardenafil?
  Vardenafil tablets marketed in the EU, including the UK, conform to the European Pharmacopoeia standards. Formulations sold in the United States may use alternative excipients but contain the same active dose. Filitra follows EU guidelines.

• How does alcohol consumption affect Filitra’s safety?
  Moderate alcohol intake (up to two standard drinks) does not significantly alter the drug’s efficacy. However, excessive alcohol can amplify vasodilatory effects, potentially leading to dizziness or low blood pressure. Patients should limit intake before sexual activity.

• What is the history of vardenafil’s development?
  Vardenafil was first approved by the FDA in 2003 under the brand name Levitra. Clinical trials demonstrated its rapid onset and high selectivity for PDE5, leading to its inclusion in treatment guidelines for erectile dysfunction worldwide.

• How does Filitra compare to sildenafil in terms of onset?
  Vardenafil (Filitra) generally produces an erection within 30 minutes, whereas sildenafil may require 45–60 minutes. Both have similar durations of effect, but individual response can vary.

• Is there a risk of false‑positive drug tests when using Filitra?
  Vardenafil is not screened for in standard workplace or sports drug tests. However, some specialized testing panels may detect PDE5 inhibitors. Patients concerned about testing should discuss this with their employer or sporting body.

• Can Filitra be taken with herbal supplements such as ginkgo biloba?
  Ginkgo biloba has mild antiplatelet activity and may theoretically increase bleeding risk, though evidence is limited. Caution is advised, and patients should consult a healthcare professional before combining the two.

Glossary

Phosphodiesterase‑type‑5 (PDE5) inhibitor

A class of drugs that block the PDE5 enzyme, increasing cGMP levels and promoting smooth‑muscle relaxation in the penis, facilitating erection.

cGMP (Cyclic guanosine monophosphate)

A intracellular messenger that mediates vasodilation; elevated levels are essential for the erectile response.

Priapism

A prolonged, often painful erection lasting more than four hours, requiring urgent medical intervention to prevent permanent tissue damage.

⚠️ Disclaimer

The information provided about Filitra is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Filitra for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.