Generic Imiquimod

Imiquimod is a topical cream used to treat genital warts, actinic keratosis, and some skin cancers by boosting the skin’s immune response. It is applied at night and washed off after several hours. Redness and irritation are common but usually temporary. Medical supervision is recommended to avoid complications.

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  • Category: Skin Care
  • Active ingredient: Imiquimod
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  • Delivery time: Airmail (10 - 21 days), EMS Trackable (5-9 days)

Buy Generic Imiquimod Online

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Generic Imiquimod information

Introduction

Imiquimod is an immune‑modulating medication classified under skin‑care agents. In the United Kingdom it is prescribed mainly for the topical treatment of certain precancerous skin lesions and external genital warts. The active compound is Imiquimod, and it is marketed by several manufacturers, including the original developer 3M™. Its therapeutic focus is to stimulate the body’s own immune response to eliminate abnormal skin cells, offering an alternative to surgical or destructive procedures.

What is Imiquimod?

Imiquimod is a synthetic imidazoquinoline compound that acts as a topical immune response modifier. It was developed in the early 199s by 3M Pharmaceuticals and was first introduced under the brand name Aldara in Europe and the United Kingdom. Other recognized brand names include Zyclara (United States) and Imiquimod Cream (generic labelling).

Imiquimod is the generic version of Aldara®, containing the same active compound Imiquimod. Our online pharmacy provides this generic alternative as a cost‑effective treatment option, meeting the same regulatory standards as the branded product.

How Imiquimod Works

Imiquimod binds to Toll‑like receptor 7 (TLR‑7) on plasmacytoid dendritic cells and macrophages in the skin. This binding triggers a signaling cascade that results in the production of cytokines such as interferon‑α, tumour necrosis factor‑α, and interleukins 6 and 12. The resulting cytokine milieu enhances both innate and adaptive immune activity:

  • Innate immunity: Activates natural killer cells and macrophages, leading to direct cytotoxicity against abnormal keratinocytes.
  • Adaptive immunity: Promotes antigen presentation and a Th1‑biased response, facilitating clearance of virus‑infected cells (e.g., HPV) and dysplastic cells.

Clinically, this immune activation manifests as local inflammation, which is the intended therapeutic effect. Lesion clearance typically begins within 2–4 weeks of consistent application, with complete remission observed after several treatment cycles depending on the indication.

Conditions Treated with Imiquimod

  • Actinic keratosis (AK): Precancerous lesions caused by chronic sun exposure. AK affects up to 30 % of individuals over 60 years in the UK, especially those with fair skin. Imiquimod reduces lesion count and prevents progression to squamous cell carcinoma.
  • Superficial basal cell carcinoma (sBCC): Early‑stage basal cell cancers confined to the epidermis. sBCC represents about 10 % of all basal cell carcinomas diagnosed in the UK. Topical Imiquimod offers a non‑surgical alternative with comparable clearance rates in selected lesions ≤2 cm.
  • External genital warts (EGW) caused by human papillomavirus (HPV) types 6 and 11: EGW prevalence is estimated at 2 % in the adult UK population. Imiquimod’s antiviral immune activation leads to wart regression without the pain associated with cryotherapy or surgical excision.

These indications are approved by the Medicines and Healthcare products Regulatory Agency (MHRA) and supported by multiple phase III clinical trials demonstrating efficacy and safety.

Who is Imiquimod For?

Imiquimod is most appropriate for adult patients (≥18 years) with:

  • Diagnosed actinic keratosis on the face or scalp, where lesions are numerous or located in cosmetically sensitive areas.
  • Superficial basal cell carcinoma ≤2 cm in diameter, where surgery would cause significant scarring or functional impairment.
  • External genital warts confirmed to be caused by low‑risk HPV subtypes, particularly when patients prefer a non‑procedural approach.

Contra‑indications include:

  • Known hypersensitivity to Imiquimod or any excipients in the cream.
  • Immunosuppressed individuals (e.g., organ‑transplant recipients, active chemotherapy) where the immune‑stimulating effect may be inadequate or pose infection risk.
  • Pregnancy or breastfeeding unless the benefits clearly outweigh potential risks; animal studies have not shown teratogenicity, but human data are limited.

Patients with extensive eczema, psoriasis, or other inflammatory skin diseases in the treatment area should discuss alternative therapies, as Imiquimod may exacerbate underlying inflammation.

Risks, Side Effects, and Interactions

Common

  • Local skin reactions: erythema, itching, burning, stinging, or soreness at the application site.
  • Crusting or flaking of treated skin.
  • Mild flu‑like symptoms (headache, fatigue) in a minority of users.

Rare

  • Hyperpigmentation or hypopigmentation persisting after treatment.
  • Development of new skin lesions unrelated to the original indication (reported in isolated case reports).
  • Severe allergic dermatitis (eczema‑like) requiring topical corticosteroids.

Serious

  • Systemic immune activation leading to severe flu‑like illness, fever >38 °C, or lymphadenopathy (rare).
  • Autoimmune flare in patients with pre‑existing autoimmune disease (e.g., lupus).
  • Secondary infection of the treated area (bacterial or fungal) if skin integrity is compromised.

Drug–Drug Interactions

  • Concomitant use of systemic immunomodulators (e.g., systemic steroids, biologics) may diminish Imiquimod efficacy.
  • Topical corticosteroids applied to the same area within 24 hours of Imiquimod can reduce therapeutic response.
  • No significant pharmacokinetic interactions are known due to minimal systemic absorption.

Patients should inform their healthcare provider of all concurrent medications, including over‑the‑counter skin products and herbal supplements.

Practical Use: Dosing, Missed Dose, Overdose

  • Actinic keratosis: Apply a thin layer of 5 % cream to the affected area once daily, five days per week (e.g., Monday–Friday) for a total of 4 weeks.
  • Superficial basal cell carcinoma: Apply 5 % cream once daily, five days per week for 6 weeks.
  • External genital warts: Apply 5 % cream three times per week (e.g., Monday, Wednesday, Friday) for up to 16 weeks, or until complete clearance.

Missed dose: Apply the missed dose as soon as remembered if the next scheduled dose is at least 12 hours away. If the missed application occurs less than 12 hours before the next dose, skip the missed dose and resume the regular schedule. Doubling the dose to compensate is not recommended.

Overdose: Due to minimal systemic absorption, toxicity from topical overdose is rare. In the event of extensive accidental application, rinse the area thoroughly with mild soap and water, and seek medical advice if severe local irritation or systemic symptoms develop.

Precautions:

  • Apply to clean, dry skin; avoid contact with eyes, mouth, or mucous membranes.
  • Do not cover the treated area with occlusive dressings unless directed by a clinician.
  • Alcohol consumption does not affect topical Imiquimod, but patients with liver disease should discuss overall medication burden with their provider.

Buying Imiquimod from Our Online Pharmacy

Imiquimod can be purchased from our online pharmacy in the UK with a streamlined ordering experience designed for patient convenience and confidentiality.

  • Affordable pricing: Our generic formulation is priced close to the manufacturer’s cost, providing a lower‑cost alternative to branded products.
  • Verified quality: All batches are sourced from licensed overseas compounding pharmacies that adhere to GMP (Good Manufacturing Practice) standards.
  • Guaranteed delivery: Discreet packaging is dispatched via express service (delivery within 7 days) or regular airmail (approximately 3 weeks), with tracking available for every order.
  • Online‑only access: We specialise in supplying international medications that may be difficult to obtain through standard UK pharmacy channels, ensuring patients who face limited access or insurance constraints can receive the treatment they need.

Our pharmacy operates as a broker service, collaborating with accredited overseas suppliers while maintaining strict privacy safeguards.

FAQ

  • Is Imiquimod available in both brand‑name and generic forms in the UK?
    Yes, Imiquimod is marketed under the original brand name Aldara® and as a generic cream containing the same active compound. The generic version offers a more economical option while meeting the same regulatory standards.

  • What is the recommended storage condition for Imiquimod cream?
    The medication should be stored at controlled room temperature (15–25 °C). It must be kept away from direct sunlight, excessive heat, and moisture, and should not be placed in bathrooms where humidity is high.

  • Can I travel internationally with a supply of Imiquimod?
    When traveling, keep the cream in its original packaging, include a copy of the pharmacy receipt, and ensure it remains within the allowed amount for personal medical use under UK export rules. Some countries may require a prescription declaration at customs.

  • Does the cream contain any allergens or preservatives that could cause irritation?
    In the UK formulation, the cream contains carbomer, polysorbate 80, and methylparaben as inactive ingredients. Patients with known hypersensitivity to these components should avoid use and consult a pharmacist for an alternative formulation if available.

  • Are there differences between the European and US formulations of Imiquimod?
    The European (including UK) and US formulations both contain 5 % Imiquimod, but excipients may vary slightly; for example, the US product may include additional stabilisers. These differences do not affect the drug’s efficacy but could influence tolerability in sensitive individuals.

  • How long does it typically take to see visible improvement in genital warts?
    Most patients notice a reduction in wart size after 4–6 weeks of consistent application, with complete clearance often achieved by week 12–16, depending on wart burden and adherence to the dosing schedule.

  • Is it safe to use Imiquimod on tattoos or cosmetic tattoos?
    Application over tattooed skin can provoke an intensified inflammatory response, potentially altering pigment appearance. It is advisable to avoid treating tattooed areas with Imiquimod unless directed by a dermatologist.

  • Can Imiquimod be used concurrently with topical retinoids for actinic keratosis?
    Combining Imiquimod with retinoids may increase skin irritation. If both treatments are required, they should be applied on alternating days under medical supervision.

  • What regulatory steps are required for personal importation of Imiquimod into the UK?
    Personal import of a medication not supplied by a UK pharmacy is permitted for a maximum three‑month supply, provided it is for personal use and accompanied by a valid prescription or a doctor's letter. Our online pharmacy assists with the necessary documentation to comply with HM Revenue & Customs rules.

  • Does Imiquimod affect standard drug testing for employment or sport?
    Imiquimod is not listed on common drug‑screening panels because it is a topical immunomodulator with negligible systemic absorption. Routine occupational or anti‑doping tests are unlikely to detect it.

Glossary

Toll‑like receptor 7 (TLR‑7)
A protein on immune cells that recognises specific molecular patterns, triggering an immune response. Imiquimod activates TLR‑7 to boost local immunity.
Actinic keratosis (AK)
Rough, scaly patches on sun‑exposed skin that represent early precancerous changes, potentially progressing to squamous cell carcinoma if untreated.
Superficial basal cell carcinoma (sBCC)
A thin, early‑stage form of basal cell skin cancer confined to the epidermis, usually presenting as a shiny, pearl‑like lesion.
Cytokine
Small signalling proteins released by immune cells that regulate inflammation and immune activity; key cytokines in Imiquimod therapy include interferon‑α and tumour necrosis factor‑α.

⚠️ Disclaimer

The information provided about Imiquimod is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Imiquimod for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.

Information about ordering Generic Imiquimod online

Buy placing an order on our website you must agree to the following: Your are above 18 years old, You do not have any contraindications to imiquimod so you can use Generic Imiquimod safely, We do not provide any paper instructions, side effect warnings or usage directions with medication Imiquimod. They are available only online on our website. We do not provide any doctors consultation -- please consult with your doctor before using this medication. We provide you a cheap alternative to save cost but we cannot replace real practioning medical specialist. When you order Generic Imiquimod without a prescription you agreee that you will get generic pills manufactured in Inida, they will be shipped to you in anonymous package except you ordered traceable delivery. From our side we guarantee quality of Generic Imiquimod - imiquimod medication that is sold through our site. We do our best and send medication in a valid condition and safely packed, however we may not guarantee worry free delivery to some countries where strict customs rules may apply. If you have questions do not hesitate to call us or use Live chat. After you place your order we may call you back for verification purposes.