Super Zhewitra

Introduction

Super Zhewitra is a combination medication that contains the phosphodiesterase‑5 inhibitor vardenafil and the short‑acting selective serotonin‑reuptake inhibitor dapoxetine. It is positioned within the Erectile Dysfunction and Men’s Health therapeutic groups and is intended for adult men living in the United Kingdom who experience difficulties achieving or maintaining an erection, premature ejaculation, or both conditions simultaneously. The dual‑action formulation addresses two of the most prevalent male sexual dysfunctions, offering a coordinated pharmacological approach that can improve sexual confidence and relationship satisfaction.

What is Super Zhewitra?

Super Zhewitra is a fixed‑dose oral tablet that combines two well‑studied active substances: vardenafil (usually 10 mg or 20 mg) and dapoxetine (usually 30 mg or 60 mg). The product is manufactured by a licensed pharmaceutical company that complies with European Union Good Manufacturing Practice (GMP) standards and holds a marketing authorisation from the UK Medicines and Healthcare products Regulatory Agency (MHRA).

Super Zhewitra is the generic version of Levitra ® (vardenafil) and Priligy ® (dapoxetine), containing the same active compounds. Our online pharmacy provides this generic alternative as a cost‑effective treatment option. The tablet’s inactive ingredients are selected to ensure stability, rapid disintegration, and acceptable taste, meeting the same quality specifications required of the original brand‑name products.

How Super Zhewitra Works

Vardenafil belongs to the phosphodiesterase‑5 (PDE5) inhibitor class. By blocking the PDE5 enzyme in the corpus cavernosum, it prevents the breakdown of cyclic guanosine monophosphate (cGMP). Elevated cGMP levels promote smooth‑muscle relaxation and increased blood flow into the penile tissue, facilitating erection when sexual stimulation is present. The onset of action is typically 30–60 minutes, with a duration of effect up to 4–5 hours.

Dapoxetine is a short‑acting SSRI that enhances serotonergic neurotransmission in the central nervous system. Its rapid absorption and short half‑life (approximately 1‑2 hours) reduce the ejaculatory latency time, allowing men to delay ejaculation for an additional 1‑2 minutes on average. Because dapoxetine is cleared quickly, it does not produce the sustained mood‑altering effects associated with longer‑acting SSRIs.

When combined, the two agents act on distinct physiological pathways—vascular erection and ejaculatory control—providing a synchronized therapeutic effect for men who experience both erectile dysfunction (ED) and premature ejaculation (PE) concurrently.

Conditions Treated with Super Zhewitra

• Erectile Dysfunction (ED) – A condition affecting an estimated 17 % of men in the UK aged 40‑70, characterised by the inability to achieve or sustain an erection sufficient for satisfactory sexual performance. Vardenafil directly addresses the vascular component of ED.
• Premature Ejaculation (PE) – The most common male sexual dysfunction, with a prevalence of 20‑30 % in the UK adult male population. Dapoxetine reduces the sensitivity of the ejaculatory reflex, extending intravaginal ejaculation latency time (IELT).

The combination is specifically indicated for men who have both ED and PE and who have not achieved satisfactory results with single‑agent therapy. Clinical guidelines from the British Association of Urological Surgeons (BAUS) and the European Association of Urology (EAU) acknowledge the potential benefit of combined therapy in selected patients, provided that safety criteria are met.

Who is Super Zhewitra For?

• Adult men (≥18 years) diagnosed with erectile dysfunction who experience a satisfactory response to PDE5 inhibitors but remain limited by premature ejaculation.
• Men with concurrent premature ejaculation who have not responded adequately to dapoxetine alone, or who prefer a single‑tablet regimen to simplify dosing.
• Individuals without contraindications to either component, such as uncontrolled hypertension, recent myocardial infarction, severe hepatic impairment, or use of nitrates.
• Patients who can adhere to the timing requirements (taking the tablet 30–60 minutes before sexual activity, with no more than one dose per 24 hours).

Super Zhewitra is not appropriate for:

• Men taking nitrates (e.g., nitroglycerin) or nitric‑oxide donors, due to risk of profound hypotension.
• Patients with a known hypersensitivity to vardenafil, dapoxetine, or any excipients.
• Individuals with severe cardiovascular disease where sexual activity is contraindicated.
• Men with congenital or acquired retinitis pigmentosa, as vardenafil may exacerbate this rare ocular condition.

Clinical assessment by a qualified healthcare professional remains essential to confirm suitability and to identify any hidden comorbidities.

Risks, Side Effects, and Interactions

Common

• Headache
• Flushing (warmth, redness of face or neck)
• Nasal congestion
• Dyspepsia (indigestion)
• Dizziness (usually mild)
• Diarrhoea (occasionally associated with dapoxetine)

These events are generally mild to moderate in intensity and resolve without medical intervention within a few hours.

Rare

• Visual disturbances (e.g., blurred vision, changes in colour perception)
• Auditory symptoms (tinnitus or hearing loss)
• Palpitations or tachycardia
• Mood changes (e.g., anxiety, irritability) linked to dapoxetine’s serotonergic activity

Patients should report any persistent or worsening symptoms to a healthcare professional promptly.

Serious

• Priapism (erection lasting >4 hours) – requires emergency medical treatment to prevent permanent penile damage.
• Severe hypotension – especially when combined with nitrates, alpha‑blockers, or potent antihypertensives.
• Serotonin syndrome – a rare but potentially life‑threatening condition when dapoxetine is used together with other serotonergic agents (e.g., tramadol, linezolid, certain antidepressants). Symptoms include agitation, hyperthermia, sweating, tremor, and muscle rigidity.

If any serious adverse event occurs, seek urgent medical care.

Clinically Relevant Drug–Drug Interactions

• Nitrates (including nitroglycerin, isosorbide dinitrate): contraindicated; may cause dangerous blood‑pressure fall.
• Alpha‑blockers (e.g., tamsulosin, doxazosin): caution; may potentiate hypotensive effect.
• Other PDE5 inhibitors: additive effect; avoid concurrent use.
• Serotonergic agents (SSRIs, SNRIs, MAO inhibitors, tramadol, St. John’s wort): risk of serotonin syndrome; dose adjustment or avoidance recommended.
• CYP3A4 inhibitors (ketoconazole, ritonavir, erythromycin): may increase vardenafil plasma levels, heightening side‑effect risk.
• CYP3A4 inducers (rifampicin, carbamazepine, phenytoin): may reduce efficacy of vardenafil.

Patients should disclose all current medications, including over‑the‑counter products and herbal supplements, before initiating therapy.

Practical Use: Dosing, Missed Dose, Overdose

• Standard starting dose: 10 mg vardenafil + 30 mg dapoxetine taken orally with water, 30–60 minutes before anticipated sexual activity. The dose may be increased to 20 mg vardenafil and/or 60 mg dapoxetine based on efficacy and tolerability, but no more than one tablet per 24 hours.
• Missed dose: If a dose is forgotten and sexual activity is not anticipated within the next 24 hours, simply skip the dose and resume the next scheduled dose. Do not double‑dose to compensate.
• Overdose: Symptoms may include pronounced hypotension, severe headache, dizziness, or prolonged erection. Seek immediate medical attention. Supportive care (intravenous fluids, blood pressure monitoring) is the mainstay of treatment; no specific antidote exists.
• Food and alcohol: A high‑fat meal can delay vardenafil absorption, extending onset to up to 2 hours. Moderate alcohol intake (≤2 units) is generally tolerated, but excessive consumption may exacerbate dizziness and hypotension.
• Renal/hepatic impairment: Dose reduction is advised for moderate hepatic dysfunction; use is not recommended in severe hepatic failure. Renal impairment does not significantly affect vardenafil clearance but may influence dapoxetine metabolism.

Buying Super Zhewitra from Our Online Pharmacy

Super Zhewitra can be safely purchased from our online pharmacy in the UK. We operate as a pharmacy‑broker service, partnering with licensed overseas suppliers that meet the stringent quality standards set by the MHRA and the European Pharmacopoeia.

• Affordability – Prices are set close to the manufacturer’s cost, providing a substantial saving compared with brand‑name equivalents.
• Verified quality – Every batch is sourced from GMP‑certified facilities and is accompanied by a full certificate of analysis.
• Discrete, reliable delivery – Orders are shipped in unmarked packaging, with express options delivering within 7 days and regular airmail arriving in approximately 3 weeks. Tracking is provided for all shipments.
• Online‑only access – Our platform offers a convenient, confidential way to obtain medications that may otherwise be difficult to source through conventional pharmacies or insurance schemes.

Patients who struggle with limited pharmacy stock, high co‑payments, or geographic barriers can benefit from this secure, cost‑effective channel.

FAQ

• Can Super Zhewitra be taken with a high‑fat meal?
  Yes, it can be taken with food, but a high‑fat meal may delay the onset of action by up to two hours. Planning the dose around meal timing can help ensure optimal effectiveness.

• What does the Super Zhewitra tablet look like?
  The tablet is typically film‑coated, round, and scored for ease of splitting. Colours and imprint codes vary by manufacturer but are designed to distinguish the 10 mg/30 mg strength from the 20 mg/60 mg version.

• Is refrigeration required for Super Zhewitra?
  No refrigeration is needed. The medication should be stored at controlled room temperature (15‑30 °C), protected from direct sunlight and moisture.

• How long can Super Zhewitra be stored after the expiry date?
  The drug’s potency cannot be guaranteed beyond the printed expiry date. Using the medication after this point may result in reduced efficacy and is not recommended.

• Can I travel internationally with Super Zhewitra?
  When travelling within the EU or to countries that recognise personal import of prescription medicines for personal use, you may carry a maximum three‑month supply. Keep the medication in its original packaging and carry a copy of the prescription or a doctor’s letter where required.

• Are there differences in formulation between UK and overseas versions?
  The active ingredients (vardenafil and dapoxetine) are identical, but excipients such as dyes or fillers may differ slightly to comply with regional regulatory guidelines. These variations do not affect therapeutic outcomes.

• What are the legal considerations for importing Super Zhewitra into the UK?
  Personal importation for a supply lasting up to three months is permitted under UK law, provided the product is for personal use and sourced from a reputable, licensed supplier. Importing larger quantities without a valid licence is illegal.

• Does Super Zhewitra show up on drug tests?
  Routine workplace drug screens typically target substances of abuse (e.g., opiates, cannabinoids). Vardenafil and dapoxetine are not part of standard detection panels, so they are unlikely to be reported as positive results.

• How was the combination of vardenafil and dapoxetine developed?
  Clinical investigations in the early 201s examined the pharmacodynamic synergy of a PDE5 inhibitor with a short‑acting SSRI. Randomised, double‑blind trials demonstrated improved sexual satisfaction scores compared with monotherapy, leading to regulatory approval of the fixed‑dose combination in several EU member states.

• What is the typical time to reach maximum blood concentration after taking Super Zhewitra?
  Peak plasma levels of vardenafil occur approximately 1 hour after oral administration, while dapoxetine reaches its maximum concentration within 1–2 hours. This overlapping pharmacokinetic profile supports simultaneous therapeutic action.

Glossary

Phosphodiesterase‑5 (PDE5) inhibitor

A class of drugs that block the enzyme responsible for degrading cGMP, thereby enhancing blood flow to the penis and facilitating erection.

Selective serotonin‑reuptake inhibitor (SSRI)

A medication that increases serotonin levels in the brain by inhibiting its reabsorption, used here to delay ejaculation.

Intravaginal ejaculation latency time (IELT)

The measured interval between vaginal penetration and ejaculation; a key endpoint in premature‑ejaculation studies.

Serotonin syndrome

A potentially life‑threatening condition resulting from excess serotonergic activity, characterised by agitation, hyperthermia, and neuromuscular abnormalities.

⚠️ Disclaimer

The information provided about Super Zhewitra is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Super Zhewitra for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.