Generic Telmisartan
Telmisartan is an ARB used to treat high blood pressure and reduce cardiovascular risks. It works by relaxing blood vessels, making it easier for the heart to pump blood. The drug is generally taken once daily and is well tolerated with proper monitoring. Consistent use is essential to maintain blood pressure control and prevent complications.
- Category: Blood Pressure
- Active ingredient: Telmisartan
- Available Dosage: 20mg, 40mg, 80mg
- Payment options: VISA, Mastercard, Amex, JCB, Dinners
- Delivery time: Airmail (10 - 21 days), EMS Trackable (5-9 days)
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Package | Price | |
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Package | Price | |
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Package | Price | |
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80mg x 180 pills Free Airmail shipping | $223.78 | |
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80mg x 60 pills | $103.90 | |
80mg x 30 pills | $63.53 |
Generic Telmisartan information
Introduction
Telmisartan is an oral antihypertensive medication widely prescribed in the United Kingdom for the management of high blood pressure and for reducing cardiovascular risk in patients with established disease. It belongs to the angiotensin II receptor blocker (ARB) class and is listed among the most frequently dispensed blood‑pressure agents in UK pharmacy data. The active compound, Telmisartan, is marketed both as a standalone generic and under well‑known brand names such as Micardis® (Boehringer Ingelheim). In addition to its primary indication for hypertension, Telmisartan is approved for use in patients with left‑ventricular hypertrophy and for secondary prevention of major cardiovascular events in high‑risk individuals.
What is Telmisartan?
Telmisartan is the generic version of Micardis®, containing the same active compound Telmisartan. It is an angiotensin II receptor blocker (ARB) that selectively inhibits the type 1 (AT₁) receptor, preventing the vasoconstrictive and proliferative actions of angiotensin II. The drug was developed by the pharmaceutical company Boehringer Ingelheim and has been approved for clinical use in the EU, including the United Kingdom, since 2005. Our online pharmacy provides this generic alternative as a cost‑effective treatment option for patients who require long‑term blood‑pressure control.
How Telmisartan Works
Telmisartan binds with high affinity to the AT₁ receptor located on vascular smooth‑muscle cells, adrenal cortex, and renal tubules. By blocking angiotensin II from activating this receptor, the drug prevents vasoconstriction, aldosterone release, and sympathetic activation. The net effect is a reduction in systemic vascular resistance and arterial pressure.
Pharmacokinetic characteristics support once‑daily dosing: the drug is rapidly absorbed (peak plasma concentrations in 1 – 2 hours), has an oral bioavailability of approximately 50 %, and is highly protein‑bound (> 99 %). Telmisartan is eliminated largely via biliary excretion with a terminal half‑life of about 24 hours, allowing sustained blood‑pressure lowering throughout a 24‑hour period.
Conditions Treated with Telmisartan
- Essential (primary) hypertension – The most common indication. Hypertension prevalence in the UK is estimated at 30 % of adults, and ARBs such as Telmisartan are recommended by NICE guidelines as first‑line therapy in patients who cannot tolerate ACE‑inhibitors or require a once‑daily regimen.
- Heart failure with reduced ejection fraction (HFrEF) – Clinical trials (e.g., the ONTARGET study) have shown that Telmisartan reduces hospitalisation for heart failure when added to standard therapy.
- Left‑ventricular hypertrophy – By attenuating angiotensin‑II‑mediated cardiac remodeling, Telmisartan helps reverse hypertrophy and improves diastolic function.
- Secondary prevention of cardiovascular events – In patients with proven atherosclerotic disease (e.g., coronary artery disease, stroke), Telmisartan reduces the risk of myocardial infarction, stroke, and cardiovascular death.
Who is Telmisartan For?
Telmisartan is appropriate for adults who:
- Have diagnosed stage 1 or stage 2 hypertension and require a once‑daily oral agent.
- Are intolerant to ACE‑inhibitors (e.g., due to cough or angio‑edema) but still need renin‑angiotensin system blockade.
- Have chronic kidney disease with stable renal function (eGFR ≥ 30 mL/min/1.73 m²) and no history of hyperkalaemia.
- Require additional cardiovascular risk reduction beyond blood‑pressure control, such as those with prior myocardial infarction or cerebrovascular disease.
Telmisartan may be unsuitable for patients with:
- Known hypersensitivity to Telmisartan or any ARB component.
- Severe hepatic impairment (Child‑Pugh class C) – limited data exist.
- Pregnancy or breastfeeding – ARBs are contraindicated owing to potential fetal toxicity.
- Concomitant use of potent CYP2C9 inhibitors (e.g., fluconazole) that could raise plasma Telmisartan concentrations.
Risks, Side Effects, and Interactions
Common
- Headache – Frequently reported, usually mild and transient.
- Dizziness or vertigo – Related to blood‑pressure lowering, especially after the first dose.
- Fatigue – Generalised tiredness without other clinical signs.
Rare
- Hyperkalaemia – Elevated serum potassium, more common in patients with renal impairment or on potassium‑sparing diuretics.
- Elevated liver enzymes – Mild transaminase elevations have been observed in isolated cases.
Serious
- Angio‑edema – Swelling of lips, tongue, or airway; requires immediate medical attention.
- Renal dysfunction – Acute kidney injury may occur in patients with bilateral renal artery stenosis or severe dehydration.
- Severe hypotension – Particularly when combined with other antihypertensives or in volume‑depleted individuals.
Drug–Drug Interactions
- Potassium‑sparing diuretics (e.g., spironolactone, amiloride) – Increase risk of hyperkalaemia.
- Non‑steroidal anti‑inflammatory drugs (NSAIDs) – May blunt antihypertensive effect and precipitate renal impairment.
- Lithium – Concurrent use can raise lithium levels, risking toxicity; close monitoring is advised.
- CYP2C9 inhibitors (e.g., fluconazole, amiodarone) – May raise Telmisartan plasma concentrations; dose adjustment may be needed.
Practical Use: Dosing, Missed Dose, Overdose
- Standard dosing – Adults typically start with 40 mg once daily; the dose may be increased to 80 mg based on blood‑pressure response and tolerability. The maximum recommended daily dose is 80 mg.
- Missed dose – If a dose is forgotten, take it as soon as remembered unless it is near the time of the next scheduled dose; then skip the missed dose and continue with the regular schedule. Do not double the dose.
- Overdose – Symptoms may include profound hypotension, dizziness, or renal dysfunction. Seek emergency medical care promptly. Supportive treatment (intravenous fluids, monitoring of blood pressure and renal function) is the mainstay of management.
- Food and alcohol – Telmisartan can be taken with or without food; high‑fat meals do not significantly affect absorption. Alcohol does not interact directly, but excessive consumption can exacerbate hypotension.
- Comorbidities – In patients with chronic kidney disease, monitor eGFR and serum potassium at baseline and periodically. For those with hepatic impairment, use the lowest effective dose and observe for signs of hepatotoxicity.
Buying Telmisartan from Our Online Pharmacy
Telmisartan can be purchased from our online pharmacy in UK with a straightforward ordering process.
- Affordable pricing – We negotiate near‑manufacturer cost, passing savings to the patient while maintaining strict quality standards.
- Verified quality – All products are sourced from licensed overseas pharmacies that comply with EU‑GMP regulations; each batch undergoes independent verification.
- Guaranteed delivery – Options include express delivery within 7 days for UK addresses and regular airmail (approximately 3 weeks) for international destinations. Packages are discreet, sealed, and labelled only with generic product information.
- Online‑only access – Our pharmacy broker service connects patients with reputable overseas suppliers, enabling a private, confidential supply chain that respects patient privacy. This model is especially valuable for individuals who lack convenient access to a local pharmacy, have limited insurance coverage, or require a generic alternative to reduce out‑of‑pocket costs.
FAQ
-
Is Telmisartan available in both brand‑name and generic forms in the UK?
Yes. The branded product Micardis® contains the same active compound as generic Telmisartan. Generic versions are typically less expensive while offering identical therapeutic efficacy. -
Does food affect the absorption of Telmisartan?
Telmisartan can be taken with or without meals; the presence of food, including high‑fat meals, has minimal impact on its bioavailability. -
What are the visual characteristics of a Telmisartan tablet?
Generic tablets are usually round, white to off‑white, and scored for easy splitting. The imprint often includes the dosage strength (e.g., “40” or “80”). -
Can Telmisartan be stored in humid environments such as a bathroom?
No. The medication should be kept at controlled room temperature (15 °C–25 °C) away from moisture, direct sunlight, and heat sources to maintain potency. -
Is Telmisartan subject to restrictions when imported for personal use in the UK?
Personal import of a three‑month supply for an individual with a valid prescription is generally permitted under UK regulations, provided the product complies with safety standards. -
Do any clinical trials compare Telmisartan with older ARBs such as losartan?
Yes. The ONTARGET and PRoFESS studies directly compared Telmisartan with losartan and demonstrated comparable blood‑pressure reduction but a more favorable effect on cardiovascular outcomes in high‑risk patients. -
What is the role of Telmisartan in renal protection?
By blocking AT₁ receptors, Telmisartan reduces intraglomerular pressure and proteinuria, offering renal protective effects, especially in patients with diabetic nephropathy. -
Are there any known differences in tablet formulation between EU and US markets?
Formulation variations may exist, such as different inactive excipients. EU‑licensed tablets commonly use lactose and microcrystalline cellulose, while US formulations may contain alternative fillers; these differences do not alter the active ingredient’s efficacy. -
Can Telmisartan be taken alongside a calcium‑channel blocker?
Yes. Combination therapy with a calcium‑channel blocker (e.g., amlodipine) is often employed for resistant hypertension; however, dosing should be adjusted under medical supervision to avoid excessive blood‑pressure lowering. -
What laboratory tests should be monitored while on Telmisartan?
Baseline and periodic monitoring of blood pressure, serum creatinine/eGFR, and potassium levels are recommended, especially in patients with renal disease, diabetes, or those using potassium‑sparing agents.
Glossary
- Angiotensin II receptor blocker (ARB)
- A class of drugs that inhibit the AT₁ receptor, preventing the actions of angiotensin II, which normally raises blood pressure and promotes vascular remodeling.
- eGFR (estimated Glomerular Filtration Rate)
- A calculation used to assess kidney function; values are expressed in mL/min/1.73 m² and guide dosing of renally excreted medications.
- Hyperkalaemia
- An elevation of serum potassium above the normal range (> 5.5 mmol/L), which can cause cardiac arrhythmias if severe.
- Pharmacy broker service
- An intermediary model where a licensed pharmacy sources medication from overseas suppliers, ensuring product authenticity while providing discreet delivery to the end‑user.
⚠️ Disclaimer
The information provided about Telmisartan is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Telmisartan for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.