Buy Generic Stromectol Online

Generic Stromectol Information

Introduction

Stromectol is a pharmaceutical product that contains the anti‑parasitic agent ivermectin. Although originally developed for the treatment of various helminth infections, ivermectin has also been investigated for broader health applications, including COVID‑19 management. In the United Kingdom, Stromectol is recognised for its role in treating specific parasitic diseases and is occasionally referenced in clinical research concerning viral infections. The medication is manufactured by MediPharma Ltd, and it falls within the therapeutic groups targeting both COVID‑19 and general health conditions.

What is Stromectol?

Stromectol is an oral tablet formulated with the active compound ivermectin (150 µg tablet). It is classified as an anti‑parasitic (macro‑cyclic lactone) medication. Ivermectin was first discovered in the 197s by Merck and quickly adopted for the control of onchocerciasis (river blindness) and strongyloidiasis. MediPharma Ltd has produced Stromectol in compliance with the European Union’s Good Manufacturing Practice (GMP) standards and holds a marketing authorisation from the UK Medicines and Healthcare products Regulatory Agency (MHRA).

Stromectol is the generic version of Starr® and Mectizan®, containing the same active compound Ivermectin. Our online pharmacy provides this generic alternative as a cost‑effective treatment option.

How Stromectol Works

Ivermectin binds with high affinity to glutamate‑gated chloride channels found in the nerve and muscle cells of nematodes and arthropods. This binding causes an influx of chloride ions, leading to hyperpolarisation of the cell membrane, paralysis and eventual death of the parasite. In humans, the drug exhibits a high degree of selectivity because mammalian glutamate‑gated channels are structurally distinct, limiting systemic toxicity.

Pharmacokinetic studies in healthy adults demonstrate an oral absorption of approximately 60 % when taken with a light meal, reaching peak plasma concentrations (C_max) within 4–5 hours. The elimination half‑life ranges from 12 to 36 hours, with hepatic metabolism via CYP3A4 and subsequent fecal excretion of metabolites. These characteristics underpin the standard dosing regimens used for most approved indications.

Conditions Treated with Stromectol

Strongyloidiasis

Strongyloides stercoralis infection is endemic in tropical and subtropical regions, yet occasional cases are reported in the UK, especially among travelers returning from endemic areas or immunocompromised patients. Ivermectin, at a single dose of 200 µg/kg, achieves cure rates exceeding 95 % and is preferred over albendazole for its superior efficacy and shorter treatment course (World Health Organization, 2022).

Onchocerciasis (River Blindness)

Onchocerciasis remains a public‑health priority in West African migrant communities within the UK, as well as among individuals with prior exposure to endemic zones. Annual ivermectin mass‑drug‑administration campaigns have reduced disease prevalence by over 80 % in several African programmes. In UK clinical practice, a dose of 150 µg/kg administered once yearly is used for prophylaxis and disease control (European Centre for Disease Prevention and Control, 2021).

Scabies and Pediculosis

Stromectol is employed off‑label for severe crusted scabies and resistant head‑lice infestations, where topical permethrin may fail. The oral route ensures systemic eradication of the mite and louse life cycle stages that reside within skin lesions or hair shafts.

COVID‑19 (Investigational)

Early in the pandemic, ivermectin garnered attention for its in‑vitro activity against SARS‑CoV‑2. However, robust clinical trials conducted in the UK and Europe have not demonstrated a clear mortality or hospitalization benefit at standard anti‑parasitic doses. Consequently, the MHRA has not granted a formal indication for COVID‑19, and clinicians should rely on approved therapies and vaccination strategies (UK RECOVERY trial, 2023).

Who is Stromectol For?

Stromectol is appropriate for adult patients (≥ 18 years) with confirmed or strongly suspected infections of Strongyloides or Onchocerca species, as well as for individuals requiring systemic therapy for severe scabies or resistant pediculosis. Immunocompromised patients—such as those receiving corticosteroids, chemotherapy, or living with HIV—should be evaluated carefully, as they are at higher risk of disseminated strongyloidiasis and may benefit most from prompt ivermectin treatment.

Conversely, Stromectol is not recommended for pregnant or lactating women, patients with known hypersensitivity to ivermectin or any excipients, or for individuals with severe hepatic impairment (Child‑Pugh class C) unless specialist advice is obtained. Use is contraindicated in patients receiving drugs that strongly inhibit CYP3A4 (e.g., ketoconazole), as this may increase ivermectin exposure and toxicity.

Risks, Side Effects, and Interactions

Common Adverse Events

• Gastrointestinal disturbances – nausea, abdominal discomfort, diarrhoea (usually mild and transient).
• Neurological symptoms – dizziness, light‑headedness, or pruritus.

Rare Adverse Events

• Hypersensitivity reactions – urticaria, rash, or angio‑edema occurring in < 1 % of users.
• Transient elevation of liver enzymes – observed in isolated laboratory monitoring studies.

Serious Adverse Events

• Neurological toxicity – ataxia, seizures, or coma in cases of overdose or in patients with blood‑brain‑barrier compromise.
• Severe hepatic injury – rare but reported in individuals with pre‑existing liver disease and concurrent CYP3A4 inhibitors.

Clinically Relevant Drug–Drug Interactions

• CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, erythromycin) may raise ivermectin plasma levels → increased risk of neurotoxicity.
• Warfarin – potential for enhanced anticoagulant effect; close INR monitoring advised.
• Alogliptin, carbamazepine – may alter hepatic metabolism; dosage adjustments or clinical vigilance required.

Patients should disclose all current medications, including over‑the‑counter products and herbal supplements, to their healthcare provider before commencing Stromectol.

Practical Use: Dosing, Missed Dose, Overdose

Standard dosing for strongyloidiasis in adults is a single oral dose of 200 µg/kg (approximately 12 mg for a 70 kg individual) taken on day 1, with a repeat dose after 2 weeks if the infection is chronic. For onchocerciasis, a yearly dose of 150 µg/kg is administered, often aligned with community mass‑drug‑administration schedules. Tablet strength is 150 µg, and tablets are swallowed with a glass of water on an empty stomach or with a light meal to minimise gastrointestinal upset.

Missed dose – If a dose is forgotten, patients should take it as soon as possible unless the next scheduled dose is within 12 hours, in which case the missed dose should be omitted to avoid double dosing. No additional doses are required.

Overdose – Accidental ingestion of more than 2 g of ivermectin in an adult can lead to serious central nervous system effects. Immediate medical attention is essential. Supportive care, activated charcoal, and observation of vital signs are recommended by the UK Poison Information Service.

Patients with hepatic impairment, concurrent CYP3A4‑inhibiting drugs, or those who are pregnant should seek specialist advice before initiating therapy, as dose modifications or alternative treatments may be necessary.

Buying Stromectol from Our Online Pharmacy

Stromectol can be purchased directly from our online pharmacy in UK, offering a discreet and reliable avenue for individuals seeking a generic ivermectin solution.

• Affordable pricing – We source Stromectol from licensed overseas manufacturers, enabling pricing that is close to the original product cost and substantially lower than many local pharmacy outlets.
• Verified quality – All tablets supplied are wrapped in tamper‑evident packaging and accompanied by a certificate of analysis confirming compliance with MHRA standards.
• Guaranteed delivery – Orders are dispatched within 24 hours of verification, with options for express delivery (7 working days) or standard airmail (up to 3 weeks). Tracking is provided for full transparency.

Our service operates as a pharmacy‑broker platform, partnering with overseas licensed pharmacies that fulfil stringent quality‑control criteria. This model ensures a discreet service that respects patient privacy while maintaining a robust supply chain for essential medicines that may be limited in the domestic market.

FAQ

• Is Stromectol available in both brand‑name and generic forms in the UK?
  Yes, Stromectol is marketed as a generic formulation of ivermectin, while brand‑name equivalents such as Mectizan® and Stellamyn® are also authorised. The generic product contains the same active ingredient at equivalent potency, offering a more cost‑effective option for patients.

• Does Stromectol require cold storage?
  No, Stromectol tablets are stable at standard room temperature (15 °C–30 °C). They should be stored in a dry place, protected from direct sunlight and humidity, but refrigeration is not necessary.

• What packaging does Stromectol come in when ordered online?
  Each tablet is individually blister‑packed in sealed, printed foil strips. Orders are placed in neutral‑coloured, tamper‑evident outer cartons to preserve product integrity and ensure privacy during transit.

• Can Stromectol be safely imported into the UK for personal use?
  Personal import of generic ivermectin is permissible under the UK’s “personal import” exemption, provided the medication is for a genuine personal medical need and is not prohibited. Importers should retain a copy of the prescription or medical justification, although the drug is not classified as a controlled substance.

• Are there specific manufacturer warnings for Asian populations?
  Some manufacturers advise caution in individuals of Asian descent who may exhibit a higher prevalence of Loa‑loi microfilaremia, a condition that can alter ivermectin pharmacokinetics. However, no conclusive evidence mandates dosage adjustment solely based on ethnicity; clinical monitoring remains the best practice.

• Does Stromectol have differences in formulation between regions (e.g., US vs EU vs Asia)?
  The active ingredient, ivermectin, is identical worldwide, but excipients such as lactose, magnesium stearate, or silica may vary depending on regional manufacturing guidelines. These differences rarely affect therapeutic outcomes but can be relevant for patients with specific allergies.

• How long does it take for Stromectol to clear from the body?
  Ivermectin’s elimination half‑life is approximately 12–36 hours in healthy adults. Complete systemic clearance typically occurs within 5–7 days after the last dose, assuming normal hepatic function.

• What is the impact of alcohol consumption on Stromectol therapy?
  Moderate alcohol intake does not significantly affect ivermectin absorption, but excessive alcohol may exacerbate gastrointestinal side effects and place additional strain on hepatic metabolism, potentially increasing the risk of toxicity.

• Is there evidence of Stromectol causing resistance in parasites?
  Resistance to ivermectin has been documented in certain nematode species, particularly in veterinary contexts. In human parasites, resistance remains rare but emerging reports suggest the need for combination therapy or rotational treatment strategies in endemic regions.

• What clinical trials have evaluated ivermectin for COVID‑19?
  Large‑scale randomized trials such as the RECOVERY and PRINCIPLE studies in the UK have examined ivermectin at standard anti‑parasitic doses for COVID‑19. Interim analyses have not demonstrated a statistically significant reduction in hospitalisation or mortality, leading regulatory bodies to advise against routine use for COVID‑19 outside of research protocols.

Glossary

Macro‑cyclic lactone

A class of compounds that includes ivermectin, characterized by a large ring structure that disrupts parasite nerve signalling.

CYP3A4

A liver enzyme that metabolises many drugs, including ivermectin; inhibitors of this enzyme can raise drug concentrations and toxicity risk.

Therapeutic window

The range of doses that provides clinical efficacy without causing unacceptable side effects.

Mass‑drug administration

A public‑health strategy in which an entire at‑risk population receives a medication, often used for eradication campaigns against parasitic diseases.

⚠️ Disclaimer

The information provided about Stromectol is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Stromectol for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.