Malignant Lymphoma

1 medicine

Malignant lymphoma is a cancer of the lymphocytes that can affect lymph nodes, the spleen, or bone marrow; treatment combines chemotherapy agents such as cyclophosphamide with radiotherapy and targeted therapy.

Cytoxan

Cyclophosphamide

50mg

Cytoxan is a oncology medication containing Cyclophosphamide, available as 50mg tablets.

from $2.63 / tablet View

Key facts

  • Malignant lymphoma is a cancer that starts in the lymphocytes, the white blood cells that form part of the immune system, and can arise in lymph nodes, the spleen, bone marrow, or other lymphatic tissue.
  • It falls into two broad families: Hodgkin's lymphoma, marked by the abnormal Reed-Sternberg cell, and non-Hodgkin's lymphoma, which covers many subtypes and is far more common.
  • Common signs are painless swollen lymph nodes in the neck, armpit, or groin, along with fever, night sweats, unexplained weight loss, and persistent fatigue.
  • Treatment combines chemotherapy, such as the alkylating agent cyclophosphamide, with radiotherapy and targeted biological therapies depending on subtype and stage.

Hodgkin's and non-Hodgkin's types

Lymphoma falls into two broad families. Hodgkin's lymphoma is characterised by a specific abnormal cell (the Reed-Sternberg cell) and tends to spread in a predictable pattern from node to node. Non-Hodgkin's lymphoma covers a wide range of subtypes and is far more common, accounting for the majority of lymphoma cases. Common signs include painless swollen lymph nodes in the neck, armpit, or groin, along with fever, night sweats, unexplained weight loss, and persistent fatigue.

How lymphoma is treated

Treatment depends on the subtype and stage. Most regimens combine several medicines; the alkylating agent cyclophosphamide is a cornerstone of many standard protocols. Radiotherapy and targeted biological therapies are often added depending on the specific diagnosis. Oncology support medicines cover a range of agents used alongside chemotherapy to manage side effects and support the body during treatment.

When to see a doctor

Anyone with persistently swollen lymph nodes or unexplained B-symptoms, fever, drenching night sweats, or significant weight loss, should seek medical assessment promptly. Early diagnosis makes treatment planning more effective and improves the range of options available.

This page is educational and does not replace advice from a doctor or pharmacist who knows your health history.